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Atomistry » Bromine » PDB 6lue-6puu » 6p8x | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 6lue-6puu » 6p8x » |
Bromine in PDB 6p8x: Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor.Protein crystallography data
The structure of Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor., PDB code: 6p8x
was solved by
C.Mohr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6p8x:
The structure of Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor. also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor.
(pdb code 6p8x). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor., PDB code: 6p8x: Jump to Bromine binding site number: 1; 2; 3; 4; Bromine binding site 1 out of 4 in 6p8xGo back to Bromine Binding Sites List in 6p8x
Bromine binding site 1 out
of 4 in the Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor.
Mono view Stereo pair view
Bromine binding site 2 out of 4 in 6p8xGo back to Bromine Binding Sites List in 6p8x
Bromine binding site 2 out
of 4 in the Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor.
Mono view Stereo pair view
Bromine binding site 3 out of 4 in 6p8xGo back to Bromine Binding Sites List in 6p8x
Bromine binding site 3 out
of 4 in the Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor.
Mono view Stereo pair view
Bromine binding site 4 out of 4 in 6p8xGo back to Bromine Binding Sites List in 6p8x
Bromine binding site 4 out
of 4 in the Crystal Structure of Human Kras G12C Covalently Bound to An Acryloylazetidine Acetamide Inhibitor.
Mono view Stereo pair view
Reference:
Y.Shin,
J.W.Jeong,
R.P.Wurz,
P.Achanta,
T.Arvedson,
M.D.Bartberger,
I.D.G.Campuzano,
R.Fucini,
S.K.Hansen,
J.Ingersoll,
J.S.Iwig,
J.R.Lipford,
V.Ma,
D.J.Kopecky,
J.Mccarter,
T.San Miguel,
C.Mohr,
S.Sabet,
A.Y.Saiki,
A.Sawayama,
S.Sethofer,
C.M.Tegley,
L.P.Volak,
K.Yang,
B.A.Lanman,
D.A.Erlanson,
V.J.Cee.
Discovery Ofn-(1-Acryloylazetidin-3-Yl)-2-(1H-Indol-1-Yl) Acetamides As Covalent Inhibitors of KRASG12C. Acs Med.Chem.Lett. V. 10 1302 2019.
Page generated: Thu Jul 11 02:22:41 2024
ISSN: ISSN 1948-5875 PubMed: 31531201 DOI: 10.1021/ACSMEDCHEMLETT.9B00258 |
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