Bromine in PDB 6php: Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution

The structure of Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution, PDB code: 6php was solved by P.A.Mroz, G.Gonzalez-Gutierrez, R.D.Dimarchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.49 / 1.65
Space group	I 41
Cell size a, b, c (Å), α, β, γ (°)	41.712, 41.712, 30.434, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 24.6

The binding sites of Bromine atom in the Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution (pdb code 6php). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution, PDB code: 6php:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Br6 b:30.2 occ:1.00 BR A:4BF6 0.0 30.2 1.0 CZ A:4BF6 1.9 25.6 1.0 CE1 A:4BF6 2.8 24.4 1.0 CE2 A:4BF6 2.8 23.7 1.0 HE1 A:4BF6 2.9 29.3 1.0 HE2 A:4BF6 3.0 28.4 1.0 CD2 A:4BF6 4.1 24.0 1.0 CD1 A:4BF6 4.1 24.6 1.0 CG A:4BF6 4.7 25.2 1.0 HD1 A:TYR10 4.8 26.7 1.0 HD1 A:4BF6 5.0 29.5 1.0 HD2 A:4BF6 5.0 28.9 1.0

Bromine binding site 2 out of 2 in the Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of Glucagon Analog with 4-Bromo-Phenylalanine Substitutions at Position 6 and 22 in Space Group I41 at 1.65 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Br22 b:24.6 occ:1.00 BR A:4BF22 0.0 24.6 1.0 CZ A:4BF22 1.9 21.0 1.0 CE1 A:4BF22 2.8 18.7 1.0 HE1 A:4BF22 2.9 22.5 1.0 CE2 A:4BF22 3.0 18.4 1.0 HE2 A:4BF22 3.1 22.1 1.0 HD21 A:LEU26 3.2 25.2 1.0 HD11 A:LEU26 3.4 24.6 1.0 CD2 A:LEU26 4.1 21.0 1.0 CD1 A:4BF22 4.1 16.6 1.0 CD2 A:4BF22 4.2 17.6 1.0 CD1 A:LEU26 4.3 20.5 1.0 HD22 A:LEU26 4.4 25.2 1.0 HG A:LEU26 4.6 24.7 1.0 HZ3 A:TRP25 4.6 27.4 1.0 CG A:LEU26 4.6 20.6 1.0 HD13 A:LEU26 4.7 24.6 1.0 CG A:4BF22 4.7 17.9 1.0 HD23 A:LEU26 4.7 25.2 1.0 HD12 A:LEU26 4.9 24.6 1.0 HD1 A:4BF22 5.0 19.9 1.0

P.A.Mroz, G.Gonzalez-Gutierrez, R.D.Dimarchi. High Resolution X-Ray Structure of Glucagon and Selected Stereo-Inversed Analogs in Novel Crystallographic Packing Arrangement. To Be Published.