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Bromine in PDB 6q49: CDK2 in Complex with FRAGLITE6Enzymatic activity of CDK2 in Complex with FRAGLITE6
All present enzymatic activity of CDK2 in Complex with FRAGLITE6:
2.7.11.22; Protein crystallography data
The structure of CDK2 in Complex with FRAGLITE6, PDB code: 6q49
was solved by
D.J.Wood,
M.P.Martin,
M.E.M.Noble,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the CDK2 in Complex with FRAGLITE6
(pdb code 6q49). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the CDK2 in Complex with FRAGLITE6, PDB code: 6q49: Bromine binding site 1 out of 1 in 6q49Go back to Bromine Binding Sites List in 6q49
Bromine binding site 1 out
of 1 in the CDK2 in Complex with FRAGLITE6
Mono view Stereo pair view
Reference:
D.J.Wood,
J.D.Lopez-Fernandez,
L.E.Knight,
I.Al-Khawaldeh,
C.Gai,
S.Lin,
M.P.Martin,
D.C.Miller,
C.Cano,
J.A.Endicott,
I.R.Hardcastle,
M.E.M.Noble,
M.J.Waring.
Fraglites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem. V. 62 3741 2019.
Page generated: Sat Dec 12 02:35:51 2020
ISSN: ISSN 0022-2623 PubMed: 30860382 DOI: 10.1021/ACS.JMEDCHEM.9B00304 |
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