Bromine in PDB 6s29: Structure of Fission Yeast MIS16-MIS19 Complex

The structure of Structure of Fission Yeast MIS16-MIS19 Complex, PDB code: 6s29 was solved by S.Lefevre, M.Korntner-Vetter, M.R.Singleton, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.28 / 1.99
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.171, 99.035, 109.880, 90.00, 98.87, 90.00
R / Rfree (%)	19.6 / 23.4

The binding sites of Bromine atom in the Structure of Fission Yeast MIS16-MIS19 Complex (pdb code 6s29). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 6 binding sites of Bromine where determined in the Structure of Fission Yeast MIS16-MIS19 Complex, PDB code: 6s29:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6;

Bromine binding site 1 out of 6 in the Structure of Fission Yeast MIS16-MIS19 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Structure of Fission Yeast MIS16-MIS19 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br501 b:29.2 occ:1.00 O A:HOH853 3.1 37.9 1.0 O A:HOH676 3.2 36.0 1.0 O A:HOH713 3.2 24.6 1.0 N A:TRP190 3.5 23.9 1.0 CA A:CYS189 3.9 26.0 1.0 O A:HOH684 3.9 36.3 1.0 CB A:ARG138 3.9 22.9 1.0 CG A:ARG138 4.0 29.7 1.0 CD A:ARG138 4.2 28.0 1.0 C A:CYS189 4.2 25.7 1.0 CD1 A:TRP190 4.2 30.9 1.0 CB A:TRP190 4.3 23.6 1.0 CB A:CYS189 4.3 26.6 1.0 O A:HOH756 4.3 33.1 1.0 CA A:TRP190 4.4 23.5 1.0 O A:TRP190 4.4 31.2 1.0 CG A:TRP190 4.7 27.2 1.0 O A:LEU188 4.8 25.6 1.0 O A:TYR139 4.8 26.9 1.0 NE A:ARG138 4.8 31.8 1.0 C A:TRP190 4.9 33.6 1.0 NE2 A:GLN57 4.9 25.2 1.0 O A:HOH822 5.0 33.1 1.0

Bromine binding site 2 out of 6 in the Structure of Fission Yeast MIS16-MIS19 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Structure of Fission Yeast MIS16-MIS19 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br502 b:30.2 occ:1.00 O A:HOH661 3.2 29.1 1.0 NH2 A:ARG312 3.4 27.9 1.0 N B:LEU79 3.4 20.0 1.0 NH1 A:ARG312 4.0 28.0 1.0 ND2 B:ASN78 4.0 20.7 1.0 O B:HOH332 4.1 33.3 1.0 CA B:ASN78 4.1 22.7 1.0 CZ A:ARG312 4.1 30.4 1.0 CB B:LEU79 4.2 19.1 1.0 CG B:LEU79 4.2 20.6 1.0 CG B:ASN78 4.2 22.6 1.0 C B:ASN78 4.2 22.5 1.0 O B:ILE77 4.4 21.0 1.0 CA B:LEU79 4.4 19.2 1.0 CD2 B:HIS80 4.4 20.4 1.0 OD1 B:ASN78 4.4 20.5 1.0 NE2 B:HIS80 4.6 17.5 1.0 N B:HIS80 4.7 22.1 1.0 CB B:ASN78 4.7 21.0 1.0 CD1 B:LEU79 4.9 16.3 1.0

Bromine binding site 3 out of 6 in the Structure of Fission Yeast MIS16-MIS19 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Structure of Fission Yeast MIS16-MIS19 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Br201 b:34.1 occ:1.00 OD1 B:ASN106 3.4 22.4 1.0 O B:ARG105 3.8 21.4 1.0 C B:ARG105 4.1 27.2 1.0 CA B:ASN106 4.1 16.9 1.0 CG B:ARG105 4.1 18.1 1.0 N B:ASN106 4.2 23.1 1.0 CB B:ALA109 4.2 21.1 1.0 O B:HOH318 4.3 31.0 1.0 CG B:ASN106 4.5 21.7 1.0 CB B:ARG105 4.6 23.2 1.0 CD B:ARG105 4.8 19.4 1.0 CB B:ASN106 4.9 12.2 1.0 CA B:ARG105 5.0 20.3 1.0

Bromine binding site 4 out of 6 in the Structure of Fission Yeast MIS16-MIS19 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Structure of Fission Yeast MIS16-MIS19 Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Br501 b:24.3 occ:1.00 O C:HOH912 3.1 36.7 1.0 O C:HOH641 3.3 24.3 1.0 N C:TRP190 3.5 19.7 1.0 CA C:CYS189 3.9 21.1 1.0 CB C:ARG138 3.9 18.3 1.0 O C:HOH701 3.9 26.5 1.0 CG C:ARG138 4.0 18.8 1.0 CD C:ARG138 4.1 23.2 1.0 CD1 C:TRP190 4.2 24.7 1.0 CB C:TRP190 4.2 21.8 1.0 C C:CYS189 4.2 20.2 1.0 CB C:CYS189 4.3 21.3 1.0 CA C:TRP190 4.4 24.6 1.0 O C:TRP190 4.5 19.9 1.0 CG C:TRP190 4.6 20.5 1.0 O C:HOH731 4.7 29.5 1.0 NE C:ARG138 4.7 28.0 1.0 O C:TYR139 4.8 21.1 1.0 O C:HOH870 4.8 31.9 1.0 O C:LEU188 4.8 21.4 1.0 C C:TRP190 4.9 20.7 1.0 NE2 C:GLN57 4.9 19.9 1.0 O C:HOH934 5.0 33.1 1.0

Bromine binding site 5 out of 6 in the Structure of Fission Yeast MIS16-MIS19 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Structure of Fission Yeast MIS16-MIS19 Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Br502 b:30.9 occ:1.00 O C:HOH703 3.3 33.0 1.0 N D:LEU79 3.3 21.4 1.0 NH2 C:ARG312 3.4 25.0 1.0 O D:HOH308 3.5 40.0 1.0 CA D:ASN78 3.9 28.2 1.0 ND2 D:ASN78 4.0 23.3 1.0 NH1 C:ARG312 4.0 22.5 1.0 CG D:ASN78 4.1 20.0 1.0 C D:ASN78 4.1 24.7 1.0 CZ C:ARG312 4.2 29.2 1.0 CG D:LEU79 4.2 22.5 1.0 CB D:LEU79 4.2 14.5 1.0 O D:ILE77 4.2 30.8 1.0 CA D:LEU79 4.3 20.9 1.0 OD1 D:ASN78 4.4 18.1 1.0 CD2 D:HIS80 4.5 21.5 1.0 CB D:ASN78 4.6 25.4 1.0 N D:HIS80 4.6 23.1 1.0 NE2 D:HIS80 4.6 21.3 1.0 CD1 D:LEU79 4.9 20.9 1.0

Bromine binding site 6 out of 6 in the Structure of Fission Yeast MIS16-MIS19 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 6 of Structure of Fission Yeast MIS16-MIS19 Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Br201 b:34.8 occ:1.00 O D:HOH368 3.1 45.0 1.0 O D:HOH335 3.2 17.5 1.0 OD1 D:ASN106 3.4 19.8 1.0 O D:ARG105 3.8 26.1 1.0 CA D:ASN106 4.1 21.6 1.0 CB D:ALA109 4.1 34.9 1.0 C D:ARG105 4.1 28.6 1.0 N D:ASN106 4.2 19.3 1.0 CG D:ARG105 4.2 23.9 1.0 CG D:ASN106 4.4 23.1 1.0 O D:HOH327 4.5 31.4 1.0 CB D:ARG105 4.6 28.2 1.0 CD D:ARG105 4.9 22.2 1.0 CB D:ASN106 4.9 17.8 1.0

M.Korntner-Vetter, S.Lefevre, X.W.Hu, R.George, M.R.Singleton. Subunit Interactions and Arrangements in the Fission Yeast MIS16-MIS18-MIS19 Complex. Life Sci Alliance V. 2 2019.
ISSN: ESSN 2575-1077
PubMed: 31371524
DOI: 10.26508/LSA.201900408