Bromine in PDB 6vrk: Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Br-Paroxetine and 8B6 Fab

The binding sites of Bromine atom in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Br-Paroxetine and 8B6 Fab (pdb code 6vrk). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Br-Paroxetine and 8B6 Fab, PDB code: 6vrk:

Bromine binding site 1 out of 1 in the Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Br-Paroxetine and 8B6 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Cryo-Em Structure of the Wild-Type Human Serotonin Transporter Complexed with Br-Paroxetine and 8B6 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Br704 b:82.0 occ:1.00 BR1 A:RFS704 0.0 82.0 1.0 C10 A:RFS704 1.9 82.0 1.0 C11 A:RFS704 2.9 82.0 1.0 C09 A:RFS704 2.9 82.0 1.0 CB A:THR497 3.5 75.2 1.0 CE1 A:PHE335 3.5 66.8 1.0 CG2 A:VAL501 3.5 77.8 1.0 CB A:VAL501 3.8 77.8 1.0 O A:THR497 3.8 75.2 1.0 C A:THR497 3.9 75.2 1.0 CZ A:PHE335 4.0 66.8 1.0 CA A:THR497 4.0 75.2 1.0 CD1 A:PHE335 4.0 66.8 1.0 CG1 A:VAL501 4.0 77.8 1.0 C08 A:RFS704 4.1 82.0 1.0 C12 A:RFS704 4.2 82.0 1.0 OG1 A:THR497 4.2 75.2 1.0 CG2 A:THR497 4.5 75.2 1.0 N A:GLY498 4.5 79.6 1.0 C07 A:RFS704 4.7 82.0 1.0 CE2 A:PHE335 4.8 66.8 1.0 CG A:PHE335 4.8 66.8 1.0 CA A:GLY498 4.9 79.6 1.0

J.A.Coleman, V.Navratna, D.Antermite, D.Yang, J.Bull, E.Gouaux. Molecular Basis For the Binding of the Antidepressant Paroxetine at the Central Site of the Human Serotonin Transporter To Be Published.