Bromine in PDB 6y3a: Structure of Plasmodium Vivax Phosphoglycerate Kinase

All present enzymatic activity of Structure of Plasmodium Vivax Phosphoglycerate Kinase:
2.7.2.3;

The structure of Structure of Plasmodium Vivax Phosphoglycerate Kinase, PDB code: 6y3a was solved by B.K.Blaszczyk, M.Hyvonen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	69.88 / 1.49
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	42.340, 84.120, 125.520, 90.00, 90.00, 90.00
R / Rfree (%)	16.3 / 19.5

The structure of Structure of Plasmodium Vivax Phosphoglycerate Kinase also contains other interesting chemical elements:

Potassium

(K)

1 atom

The binding sites of Bromine atom in the Structure of Plasmodium Vivax Phosphoglycerate Kinase (pdb code 6y3a). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Structure of Plasmodium Vivax Phosphoglycerate Kinase, PDB code: 6y3a:

Bromine binding site 1 out of 1 in the Structure of Plasmodium Vivax Phosphoglycerate Kinase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Structure of Plasmodium Vivax Phosphoglycerate Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Br502 b:51.9 occ:1.00 OG1 A:THR297 3.2 22.3 1.0 CA A:LYS298 3.5 19.5 1.0 N A:LYS298 3.7 19.5 1.0 C A:THR297 3.8 20.1 1.0 C A:LYS298 3.9 17.4 1.0 O A:THR297 3.9 21.9 1.0 CB A:THR297 3.9 19.7 1.0 CE A:LYS286 4.0 25.3 1.0 O A:HOH800 4.3 41.5 1.0 O A:LYS298 4.3 19.4 1.0 CG2 A:VAL299 4.4 19.6 1.0 N A:VAL299 4.4 19.1 1.0 CG A:LYS286 4.5 19.6 1.0 CA A:THR297 4.5 20.1 1.0 CD A:LYS286 4.6 22.3 1.0 NZ A:LYS286 4.7 25.5 1.0 O A:HOH739 4.7 41.8 1.0 O A:HOH896 4.8 24.7 1.0 CB A:LYS298 4.9 23.5 1.0

E.Bilsland, F.Costa, B.K.Blaszczyk, M.Hyvonen, P.Sunnerhagen. Phosphoglycerate Kinase As A Potential Target For Antimalarial Therapy To Be Published.