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Bromine in PDB 7a1z: Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]PyridineEnzymatic activity of Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine
All present enzymatic activity of Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine, PDB code: 7a1z
was solved by
K.Niefind,
D.Lindenblatt,
C.Toelzer,
M.Bretner,
K.Chojnacki,
M.Wielechowska,
P.Winska,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7a1z:
The structure of Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine
(pdb code 7a1z). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine, PDB code: 7a1z: Bromine binding site 1 out of 1 in 7a1zGo back to Bromine Binding Sites List in 7a1z
Bromine binding site 1 out
of 1 in the Crystal Structure of Human Protein Kinase CK2ALPHA' (CSNK2A2 Gene Product) in Complex with the Atp-Competitive Inhibitor 6-Bromo-5- Chloro-1H-Triazolo[4,5-B]Pyridine
Mono view Stereo pair view
Reference:
K.Chojnacki,
D.Lindenblatt,
P.Winska,
M.Wielechowska,
C.Toelzer,
K.Niefind,
M.Bretner.
Synthesis, Biological Properties and Structural Study of New Halogenated Azolo[4,5-B]Pyridines As Inhibitors of CK2 Kinase Bioorg.Chem. 2020.
Page generated: Sat Dec 12 02:43:53 2020
ISSN: ISSN 0045-2068 DOI: 10.1016/J.BIOORG.2020.104502 |
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