Bromine in PDB 7blb: BAZ2A Bromodomain in Complex with GSK4027 Chemical Probe

The structure of BAZ2A Bromodomain in Complex with GSK4027 Chemical Probe, PDB code: 7blb was solved by A.Dalle Vedove, G.Cazzanelli, A.Caflisch, G.Lolli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.04 / 2.30
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	94.089, 94.089, 33.34, 90, 90, 120
R / Rfree (%)	20 / 22.6

The binding sites of Bromine atom in the BAZ2A Bromodomain in Complex with GSK4027 Chemical Probe (pdb code 7blb). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the BAZ2A Bromodomain in Complex with GSK4027 Chemical Probe, PDB code: 7blb:

Bromine binding site 1 out of 1 in the BAZ2A Bromodomain in Complex with GSK4027 Chemical Probe


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of BAZ2A Bromodomain in Complex with GSK4027 Chemical Probe within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1901 b:66.9 occ:0.72 BR A:9ST1901 0.0 66.9 0.7 C43 A:9ST1901 1.9 47.4 0.7 C32 A:9ST1901 2.9 43.4 0.7 C41 A:9ST1901 3.0 39.6 0.7 O A:PRO1817 3.1 35.6 1.0 O42 A:9ST1901 3.1 35.2 0.7 N30 A:9ST1901 3.2 45.7 0.7 O A:HOH2013 3.5 37.5 1.0 O A:HOH2019 3.7 36.2 1.0 CG2 A:VAL1822 3.7 42.5 1.0 O A:HOH2017 3.8 26.0 1.0 CB A:PRO1817 3.9 34.6 1.0 O A:HOH2010 3.9 37.0 1.0 CD1 A:PHE1818 3.9 28.2 1.0 CE1 A:PHE1818 3.9 29.0 1.0 C A:PRO1817 3.9 34.5 1.0 CG1 A:VAL1879 4.2 31.5 1.0 N36 A:9ST1901 4.3 33.1 0.7 C33 A:9ST1901 4.3 48.0 0.7 CA A:PRO1817 4.4 33.1 1.0 C09 A:9ST1901 4.6 46.7 0.7 N35 A:9ST1901 4.9 42.8 0.7 N A:PHE1818 4.9 32.2 1.0

G.Cazzanelli, A.Dalle Vedove, V.G.D'agostino, A.Caflisch, G.Lolli. Chemical Probes in the BAZ2A Bromodomain To Be Published.