Bromine in PDB 7ej8: Structure of the ALPHA2A-Adrenergic Receptor Goa Signaling Complex Bound to Brimonidine

The binding sites of Bromine atom in the Structure of the ALPHA2A-Adrenergic Receptor Goa Signaling Complex Bound to Brimonidine (pdb code 7ej8). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Structure of the ALPHA2A-Adrenergic Receptor Goa Signaling Complex Bound to Brimonidine, PDB code: 7ej8:

Bromine binding site 1 out of 1 in the Structure of the ALPHA2A-Adrenergic Receptor Goa Signaling Complex Bound to Brimonidine


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Structure of the ALPHA2A-Adrenergic Receptor Goa Signaling Complex Bound to Brimonidine within 5.0Å range: probe atom residue distance (Å) B Occ R:Br501 b:135.9 occ:1.00 BR1 R:J59501 0.0 135.9 1.0 C8 R:J59501 1.9 135.9 1.0 C7 R:J59501 2.9 135.9 1.0 C9 R:J59501 2.9 135.9 1.0 N5 R:J59501 3.0 135.9 1.0 N10 R:J59501 3.1 135.9 1.0 N6 R:J59501 3.1 135.9 1.0 C4 R:J59501 3.1 135.9 1.0 CB R:CYS132 3.2 107.9 1.0 SG R:CYS132 3.6 107.9 1.0 C1 R:J59501 4.0 135.9 1.0 N3 R:J59501 4.2 135.9 1.0 C14 R:J59501 4.2 135.9 1.0 C16 R:J59501 4.2 135.9 1.0 CH2 R:TRP402 4.3 117.6 1.0 CZ3 R:TRP402 4.3 117.6 1.0 C11 R:J59501 4.4 135.9 1.0 CA R:VAL129 4.4 122.0 1.0 OD2 R:ASP128 4.5 125.7 1.0 CA R:CYS132 4.5 107.9 1.0 C2 R:J59501 4.6 135.9 1.0 O R:VAL129 4.7 122.0 1.0 O R:ASP128 4.7 125.7 1.0 C15 R:J59501 4.7 135.9 1.0 CZ R:PHE406 4.7 127.4 1.0 C R:CYS132 5.0 107.9 1.0 N R:THR133 5.0 107.4 1.0 CE2 R:PHE405 5.0 131.2 1.0

J.Xu, S.Cao, H.Hubner, D.Weikert, G.Chen, Q.Lu, D.Yuan, P.Gmeiner, Z.Liu, Y.Du. Structural Insights Into Ligand Recognition, Activation, and Signaling of the Alpha 2A Adrenergic Receptor. Sci Adv V. 8 J5347 2022.
ISSN: ESSN 2375-2548
PubMed: 35245122
DOI: 10.1126/SCIADV.ABJ5347