Bromine in PDB 7k30: Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site

The structure of Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site, PDB code: 7k30 was solved by K.Shi, N.M.Moeller, S.Banerjee, L.Yin, K.Orellana, H.Aihara, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	88.12 / 2.34
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	152.7, 152.7, 118.17, 90, 90, 120
R / Rfree (%)	20.6 / 22.8

The structure of Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Magnesium	(Mg)	1 atom

The binding sites of Bromine atom in the Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site (pdb code 7k30). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site, PDB code: 7k30:

Bromine binding site 1 out of 1 in the Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Endonuclease Q Complex with 27-Mer Duplex Substrate with Du at the Active Site within 5.0Å range: probe atom residue distance (Å) B Occ B:Br16 b:150.6 occ:1.00 BR B:BRU16 0.0 150.6 1.0 C5 B:BRU16 1.9 118.1 1.0 C6 B:BRU16 2.8 96.4 1.0 C4 B:BRU16 2.9 105.4 1.0 O4 B:BRU16 3.0 98.4 1.0 N4 B:DC17 3.4 107.3 1.0 C8 B:DG15 3.5 97.5 1.0 N7 B:DG15 3.7 92.9 1.0 N9 B:DG15 3.9 98.7 1.0 O B:HOH103 3.9 47.4 1.0 C4 B:DC17 4.1 104.6 1.0 C5 B:DG15 4.1 92.1 1.0 N1 B:BRU16 4.1 84.7 1.0 N3 B:BRU16 4.2 97.6 1.0 C4 B:DG15 4.2 96.6 1.0 C2' B:DG15 4.2 98.4 1.0 C5 B:DC17 4.4 97.5 1.0 O6 C:DG11 4.5 83.1 1.0 C1' B:DG15 4.5 93.0 1.0 C2 B:BRU16 4.7 94.4 1.0 N3 B:DC17 4.9 104.7 1.0 C6 B:DG15 4.9 89.0 1.0

K.Shi, N.H.Moeller, S.Banerjee, J.L.Mccann, M.A.Carpenter, L.Yin, R.Moorthy, K.Orellana, D.A.Harki, R.S.Harris, H.Aihara. Structural Basis For Recognition of Distinct Deaminated Dna Lesions By Endonuclease Q. Proc.Natl.Acad.Sci.Usa V. 118 2021.
ISSN: ESSN 1091-6490
PubMed: 33658373
DOI: 10.1073/PNAS.2021120118