Atomistry » Bromine » PDB 7i1d-7md6 » 7k6r
Atomistry »
  Bromine »
    PDB 7i1d-7md6 »
      7k6r »

Bromine in PDB 7k6r: Crystal Structure of the Bromodomain (Bd) of Human Bromodomain and Phd Finger-Containing Transcription Factor (Bptf) Bound to GSK4027

Protein crystallography data

The structure of Crystal Structure of the Bromodomain (Bd) of Human Bromodomain and Phd Finger-Containing Transcription Factor (Bptf) Bound to GSK4027, PDB code: 7k6r was solved by A.Chan, E.Schonbrunn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.28 / 1.60
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 27.060, 35.520, 41.150, 114.12, 95.93, 91.06
R / Rfree (%) 16.1 / 19.7

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of the Bromodomain (Bd) of Human Bromodomain and Phd Finger-Containing Transcription Factor (Bptf) Bound to GSK4027 (pdb code 7k6r). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of the Bromodomain (Bd) of Human Bromodomain and Phd Finger-Containing Transcription Factor (Bptf) Bound to GSK4027, PDB code: 7k6r:

Bromine binding site 1 out of 1 in 7k6r

Go back to Bromine Binding Sites List in 7k6r
Bromine binding site 1 out of 1 in the Crystal Structure of the Bromodomain (Bd) of Human Bromodomain and Phd Finger-Containing Transcription Factor (Bptf) Bound to GSK4027


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of the Bromodomain (Bd) of Human Bromodomain and Phd Finger-Containing Transcription Factor (Bptf) Bound to GSK4027 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br3101

b:18.5
occ:1.00
BR A:9ST3101 0.0 18.5 1.0
C43 A:9ST3101 1.9 13.0 1.0
C32 A:9ST3101 2.9 14.7 1.0
C41 A:9ST3101 2.9 16.5 1.0
O42 A:9ST3101 3.1 17.1 1.0
N30 A:9ST3101 3.2 16.6 1.0
O A:PRO2951 3.4 16.1 1.0
CE1 A:PHE2952 3.5 16.4 1.0
CD1 A:PHE2952 3.7 15.8 1.0
O A:HOH3210 3.7 16.5 1.0
CB A:PRO2951 3.7 15.0 1.0
O A:HOH3244 3.8 15.9 1.0
C A:PRO2951 4.0 13.6 1.0
O A:HOH3259 4.2 17.6 1.0
N36 A:9ST3101 4.3 19.8 1.0
CG2 A:VAL2956 4.3 17.9 1.0
C33 A:9ST3101 4.3 18.0 1.0
CB A:PHE3013 4.3 17.4 1.0
CG A:PHE3013 4.3 18.3 1.0
O A:HOH3264 4.3 17.1 1.0
SG A:CYS3003 4.3 15.0 1.0
CA A:PRO2951 4.4 14.7 1.0
CD1 A:PHE3013 4.4 18.1 1.0
CZ A:PHE2952 4.5 15.8 1.0
C09 A:9ST3101 4.6 17.4 1.0
CG A:PHE2952 4.7 12.1 1.0
CD2 A:PHE3013 4.8 19.7 1.0
N35 A:9ST3101 4.8 22.2 1.0
CB A:CYS3003 4.8 13.5 1.0
N A:PHE2952 4.9 14.2 1.0

Reference:

P.D.Ycas, H.Zahid, A.Chan, N.M.Olson, J.A.Johnson, S.K.Talluri, E.Schonbrunn, W.C.K.Pomerantz. New Inhibitors For the Bptf Bromodomain Enabled By Structural Biology and Biophysical Assay Development. Org.Biomol.Chem. V. 18 5174 2020.
ISSN: ESSN 1477-0539
PubMed: 32588860
DOI: 10.1039/D0OB00506A
Page generated: Mon Jul 7 11:24:36 2025

Last articles

Ca in 1KEC
Ca in 1KDQ
Ca in 1KCL
Ca in 1KDM
Ca in 1KBC
Ca in 1KCK
Ca in 1K9U
Ca in 1KBK
Ca in 1KBB
Ca in 1KB3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy