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Bromine in PDB 7mda: Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1
Enzymatic activity of Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1
All present enzymatic activity of Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1:
2.5.1.48; 4.4.1.1; 4.4.1.8;
2.5.1.48; 4.4.1.1; 4.4.1.8;
Protein crystallography data
The structure of Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1, PDB code: 7mda
was solved by
A.Nuthanakanti,
A.Serganov,
A.Kaushik,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.95 / 2.24 |
| Space group | I 41 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 105.227, 105.227, 287.668, 90, 90, 90 |
| R / Rfree (%) | 18.4 / 21.1 |
Other elements in 7mda:
The structure of Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1 also contains other interesting chemical elements:
| Sodium | (Na) | 2 atoms |
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1
(pdb code 7mda). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1, PDB code: 7mda:
Jump to Bromine binding site number: 1; 2;
In total 2 binding sites of Bromine where determined in the Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1, PDB code: 7mda:
Jump to Bromine binding site number: 1; 2;
Bromine binding site 1 out of 2 in 7mda
Go back to
Bromine Binding Sites List in 7mda
Bromine binding site 1 out
of 2 in the Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1 within 5.0Å range:
|
Bromine binding site 2 out of 2 in 7mda
Go back to
Bromine Binding Sites List in 7mda
Bromine binding site 2 out
of 2 in the Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Crystal Structure of Staphylococcus Aureus Cystathionine Gamma Lyase Holoenzyme Y103A Mutant Co-Crystallized with NL1 within 5.0Å range:
|
Reference:
K.Shatalin,
A.Nuthanakanti,
A.Kaushik,
D.Shishov,
A.Peselis,
I.Shamovsky,
B.Pani,
M.Lechpammer,
N.Vasilyev,
E.Shatalina,
D.Rebatchouk,
A.Mironov,
P.Fedichev,
A.Serganov,
E.Nudler.
Inhibitors of Bacterial H 2 S Biogenesis Targeting Antibiotic Resistance and Tolerance. Science V. 372 1169 2021.
ISSN: ESSN 1095-9203
PubMed: 34112687
DOI: 10.1126/SCIENCE.ABD8377
Page generated: Thu Jul 11 04:06:28 2024
ISSN: ESSN 1095-9203
PubMed: 34112687
DOI: 10.1126/SCIENCE.ABD8377
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