Atomistry » Bromine » PDB 7q2e-7stu » 7qc1
Atomistry »
  Bromine »
    PDB 7q2e-7stu »
      7qc1 »

Bromine in PDB 7qc1: Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436

Enzymatic activity of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436

All present enzymatic activity of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436:
6.1.1.15;

Protein crystallography data

The structure of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436, PDB code: 7qc1 was solved by C.Johansson, M.Tye, N.C.Payne, R.Mazitschek, U.C.T.Oppermann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 65.53 / 2.51
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 207.21, 207.21, 115.85, 90, 90, 90
R / Rfree (%) 19.1 / 23.3

Other elements in 7qc1:

The structure of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436 also contains other interesting chemical elements:

Chlorine (Cl) 3 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436 (pdb code 7qc1). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 3 binding sites of Bromine where determined in the Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436, PDB code: 7qc1:
Jump to Bromine binding site number: 1; 2; 3;

Bromine binding site 1 out of 3 in 7qc1

Go back to Bromine Binding Sites List in 7qc1
Bromine binding site 1 out of 3 in the Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br801

b:83.5
occ:1.00
BR A:9XM801 0.0 83.5 1.0
C1 A:9XM801 1.9 70.6 1.0
C2 A:9XM801 2.8 63.8 1.0
C A:9XM801 2.9 62.8 1.0
CL A:9XM801 3.3 60.7 1.0
CG1 A:VAL339 3.5 82.9 1.0
CB A:PRO358 3.8 55.7 1.0
C A:GLU338 3.8 79.7 1.0
N A:VAL339 3.9 70.8 1.0
CG A:PRO358 4.0 55.1 1.0
N A:GLU338 4.0 98.3 1.0
O A:GLU338 4.1 68.2 1.0
C3 A:9XM801 4.1 63.9 1.0
C35 A:9XM801 4.2 55.8 1.0
CA A:GLU338 4.2 89.3 1.0
CB A:GLU338 4.3 93.9 1.0
CA A:VAL339 4.3 73.3 1.0
O A:HOH909 4.3 88.1 1.0
CG A:ARG390 4.5 59.7 1.0
CB A:VAL339 4.5 71.3 1.0
C34 A:9XM801 4.7 56.4 1.0
N A:PRO337 4.8 102.3 1.0
CB A:ARG390 4.8 57.6 1.0
OE1 A:GLU338 5.0 103.7 1.0

Bromine binding site 2 out of 3 in 7qc1

Go back to Bromine Binding Sites List in 7qc1
Bromine binding site 2 out of 3 in the Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Br801

b:106.9
occ:1.00
BR D:9XM801 0.0 106.9 1.0
C1 D:9XM801 1.9 84.5 1.0
C2 D:9XM801 2.8 78.6 1.0
C D:9XM801 2.9 81.9 1.0
CL D:9XM801 3.3 83.5 1.0
CG1 D:VAL339 3.4 90.2 1.0
CG D:GLU338 3.6 107.8 1.0
O D:SER336 3.7 125.3 1.0
CB D:PRO358 3.8 66.0 1.0
C D:GLU338 4.0 103.4 1.0
N D:VAL339 4.1 103.1 1.0
N D:GLU338 4.1 124.6 1.0
CG D:PRO358 4.1 73.0 1.0
C3 D:9XM801 4.1 77.5 1.0
O D:HOH903 4.2 95.1 1.0
C35 D:9XM801 4.2 73.6 1.0
O D:GLU338 4.2 85.5 1.0
CA D:VAL339 4.4 102.4 1.0
CA D:GLU338 4.4 111.7 1.0
CB D:VAL339 4.5 95.1 1.0
CG D:ARG390 4.6 70.9 1.0
OE2 D:GLU338 4.6 114.5 1.0
CB D:GLU338 4.6 101.6 1.0
C34 D:9XM801 4.7 72.7 1.0
CD D:GLU338 4.7 117.1 1.0
CB D:ARG390 4.8 66.1 1.0
C D:SER336 4.9 136.7 1.0

Bromine binding site 3 out of 3 in 7qc1

Go back to Bromine Binding Sites List in 7qc1
Bromine binding site 3 out of 3 in the Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436 within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Br801

b:89.9
occ:1.00
BR I:9XM801 0.0 89.9 1.0
C1 I:9XM801 1.9 66.5 1.0
C2 I:9XM801 2.8 68.5 1.0
C I:9XM801 2.9 63.8 1.0
CL I:9XM801 3.3 69.0 1.0
CG2 I:VAL339 3.6 95.4 1.0
O I:GLU338 3.9 84.4 1.0
CB I:PRO358 3.9 65.7 1.0
C I:GLU338 4.0 93.6 1.0
CG I:PRO358 4.1 56.0 1.0
CB I:GLU338 4.1 83.0 1.0
C3 I:9XM801 4.1 59.0 1.0
C35 I:9XM801 4.2 67.0 1.0
N I:VAL339 4.4 91.2 1.0
N I:SER336 4.5 99.7 1.0
CA I:GLU338 4.5 94.5 1.0
CG I:ARG390 4.6 58.4 1.0
CA I:VAL339 4.6 87.1 1.0
C34 I:9XM801 4.7 57.3 1.0
CB I:VAL339 4.7 83.5 1.0
N I:GLU338 4.8 102.6 1.0

Reference:

C.Johansson, M.Tye, N.C.Payne, R.Mazitschek, U.C.T.Oppermann. Crystal Structure of Prolyl-Trna Synthetase (Prors, Proline-Trna Ligase) From Plasmodium Falciparum in Complex with MAT436 To Be Published.
Page generated: Thu Jul 11 04:24:03 2024

Last articles

Zn in 2YRC
Zn in 2YQP
Zn in 2YR2
Zn in 2YQL
Zn in 2YPT
Zn in 2YPA
Zn in 2YPU
Zn in 2YNW
Zn in 2YNT
Zn in 2YNV
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy