Bromine in PDB 7s3a: Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide

Protein crystallography data

The structure of Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide, PDB code: 7s3a was solved by J.L.Jenkins, S.Henderson, C.L.Kielkopf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.76 / 1.48
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 43.245, 63.022, 77.491, 90, 90, 90
R / Rfree (%) 13.1 / 15.7

Other elements in 7s3a:

The structure of Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide also contains other interesting chemical elements:

Sodium (Na) 3 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide (pdb code 7s3a). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide, PDB code: 7s3a:

Bromine binding site 1 out of 1 in 7s3a

Go back to Bromine Binding Sites List in 7s3a
Bromine binding site 1 out of 1 in the Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-C5 Oligonucleotide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Br7

b:24.4
occ:1.00
BR B:BRU7 0.0 24.4 1.0
C5 B:BRU7 1.9 17.3 1.0
NA B:NA101 2.1 25.9 1.0
C6 B:BRU7 2.9 16.9 1.0
H6 B:BRU7 2.9 20.3 1.0
C4 B:BRU7 3.0 15.7 1.0
O4 B:BRU7 3.2 15.8 1.0
H3' B:U6 3.4 19.8 1.0
OP2 B:U6 3.5 16.6 1.0
O5' B:U6 3.5 15.4 1.0
O B:HOH222 3.8 20.7 1.0
CE1 A:TYR152 3.8 13.1 1.0
HE1 A:TYR152 3.9 15.7 1.0
CZ A:TYR152 3.9 13.9 1.0
P B:U6 3.9 16.0 1.0
HG3 A:ARG227 3.9 15.7 1.0
O A:HOH572 3.9 19.8 1.0
HE1 A:HIS230 3.9 21.2 1.0
OH A:TYR152 4.0 15.1 1.0
H2' B:U6 4.0 20.1 1.0
O B:HOH224 4.0 22.0 1.0
N1 B:BRU7 4.1 15.5 1.0
N3 B:BRU7 4.2 13.8 1.0
H5'' B:U6 4.2 19.1 1.0
C3' B:U6 4.3 16.5 1.0
OP1 B:U6 4.4 16.8 1.0
NE2 A:HIS230 4.4 18.9 1.0
CE1 A:HIS230 4.4 17.7 1.0
C5' B:U6 4.4 15.9 1.0
CD1 A:TYR152 4.4 13.9 1.0
CE2 A:TYR152 4.5 14.3 1.0
HO2' B:U6 4.6 22.3 1.0
C2' B:U6 4.6 16.8 1.0
O B:HOH209 4.7 23.1 1.0
C2 B:BRU7 4.7 14.3 1.0
HH A:TYR152 4.8 18.1 1.0
HD1 A:TYR152 4.8 16.7 1.0
HE2 A:TYR152 4.8 17.2 1.0
O5' B:BRU7 4.9 17.9 1.0
CG A:ARG227 4.9 13.1 1.0
CD2 A:TYR152 5.0 12.8 1.0
CG A:TYR152 5.0 12.8 1.0
C4' B:U6 5.0 16.8 1.0

Reference:

E.Glasser, D.Maji, G.Biancon, A.M.K.Puthenpeedikakkal, C.E.Cavender, T.Tebaldi, J.L.Jenkins, D.H.Mathews, S.Halene, C.L.Kielkopf. Pre-Mrna Splicing Factor U2AF2 Recognizes Distinct Conformations of Nucleotide Variants at the Center of the Pre-Mrna Splice Site Signal. Nucleic Acids Res. V. 50 5299 2022.
ISSN: ESSN 1362-4962
PubMed: 35524551
DOI: 10.1093/NAR/GKAC287
Page generated: Tue Apr 4 17:37:57 2023

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