Bromine in PDB 7vr7: Inward-Facing Structure of Human EAAT2 in the WAY213613-Bound State

The structure of Inward-Facing Structure of Human EAAT2 in the WAY213613-Bound State also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Bromine atom in the Inward-Facing Structure of Human EAAT2 in the WAY213613-Bound State (pdb code 7vr7). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Inward-Facing Structure of Human EAAT2 in the WAY213613-Bound State, PDB code: 7vr7:

Bromine binding site 1 out of 1 in the Inward-Facing Structure of Human EAAT2 in the WAY213613-Bound State


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Inward-Facing Structure of Human EAAT2 in the WAY213613-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1001 b:170.1 occ:1.00 BR A:GJ01001 0.0 170.1 1.0 C23 A:GJ01001 1.9 153.5 1.0 C25 A:GJ01001 2.8 150.8 1.0 C6 A:GJ01001 3.0 145.8 1.0 O7 A:GJ01001 3.1 137.2 1.0 OD2 A:ASP471 3.8 112.3 1.0 C2 A:GJ01001 4.1 146.9 1.0 CD1 A:LEU447 4.2 60.9 1.0 CG2 A:VAL468 4.2 82.4 1.0 CG1 A:VAL468 4.2 82.2 1.0 CG A:ASP471 4.2 112.7 1.0 C5 A:GJ01001 4.3 145.9 1.0 C8 A:GJ01001 4.4 131.8 1.0 CB A:VAL468 4.5 80.4 1.0 CA A:VAL468 4.5 79.4 1.0 CB A:ASP471 4.6 105.9 1.0 C9 A:GJ01001 4.6 134.2 1.0 C3 A:GJ01001 4.7 146.3 1.0 OD1 A:ASP471 4.8 115.4 1.0 CB A:LEU447 5.0 54.6 1.0

T.Kato, T.Kusakizako, C.Jin, X.Zhou, R.Ohgaki, L.Quan, M.Xu, S.Okuda, K.Kobayashi, K.Yamashita, T.Nishizawa, Y.Kanai, O.Nureki. Structural Insights Into Inhibitory Mechanism of Human Excitatory Amino Acid Transporter EAAT2. Nat Commun V. 13 4714 2022.
ISSN: ESSN 2041-1723
PubMed: 35953475
DOI: 10.1038/S41467-022-32442-6