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Bromine in PDB 8csg: Human PRMT5:MEP50 Structure with Fragment 1 and Mta BoundEnzymatic activity of Human PRMT5:MEP50 Structure with Fragment 1 and Mta Bound
All present enzymatic activity of Human PRMT5:MEP50 Structure with Fragment 1 and Mta Bound:
2.1.1.320; Protein crystallography data
The structure of Human PRMT5:MEP50 Structure with Fragment 1 and Mta Bound, PDB code: 8csg
was solved by
R.J.Gunn,
J.D.Lawson,
C.R.Smith,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Human PRMT5:MEP50 Structure with Fragment 1 and Mta Bound
(pdb code 8csg). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Human PRMT5:MEP50 Structure with Fragment 1 and Mta Bound, PDB code: 8csg: Bromine binding site 1 out of 1 in 8csgGo back to Bromine Binding Sites List in 8csg
Bromine binding site 1 out
of 1 in the Human PRMT5:MEP50 Structure with Fragment 1 and Mta Bound
Mono view Stereo pair view
Reference:
C.R.Smith,
S.Kulyk,
M.U.D.Ahmad,
V.Arkhipova,
J.G.Christensen,
R.J.Gunn,
A.Ivetac,
J.M.Ketcham,
J.Kuehler,
J.D.Lawson,
N.C.Thomas,
X.Wang,
M.A.Marx.
Fragment Optimization and Elaboration Strategies - the Discovery of Two Lead Series of PRMT5/Mta Inhibitors From Five Fragment Hits Rsc Med Chem 2022.
Page generated: Tue Apr 4 17:44:57 2023
ISSN: ESSN 2632-8682 DOI: 10.1039/D2MD00163B |
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