Atomistry » Bromine » PDB 8jfx-8px8 » 8kg5
Atomistry »
  Bromine »
    PDB 8jfx-8px8 »
      8kg5 »

Bromine in PDB 8kg5: Prefusion Rsv F Bound to Lonafarnib and D25 Fab

Other elements in 8kg5:

The structure of Prefusion Rsv F Bound to Lonafarnib and D25 Fab also contains other interesting chemical elements:

Chlorine (Cl) 3 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab (pdb code 8kg5). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 6 binding sites of Bromine where determined in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab, PDB code: 8kg5:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6;

Bromine binding site 1 out of 6 in 8kg5

Go back to Bromine Binding Sites List in 8kg5
Bromine binding site 1 out of 6 in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Prefusion Rsv F Bound to Lonafarnib and D25 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br601

b:94.7
occ:1.00
 BR37 A:336601 0.0 94.7 1.0
C29 A:336601 1.9 94.7 1.0
C17 A:336601 2.9 94.7 1.0
C30 A:336601 2.9 94.7 1.0
O A:GLY139 2.9 57.0 1.0
C A:GLY139 3.3 57.0 1.0
CA A:GLY139 3.7 57.0 1.0
N A:PHE140 4.0 56.9 1.0
C35 B:336601 4.1 93.1 1.0
C28 B:336601 4.2 93.1 1.0
C41 A:336601 4.2 94.7 1.0
N32 A:336601 4.2 94.7 1.0
C19 B:336601 4.2 93.1 1.0
C40 B:336601 4.3 93.1 1.0
C20 B:336601 4.3 93.1 1.0
C42 B:336601 4.3 93.1 1.0
C6 B:336601 4.5 93.1 1.0
CA A:PHE140 4.6 56.9 1.0
C39 A:336601 4.7 94.7 1.0
CD A:GLN354 4.7 57.9 1.0
CG A:GLN354 4.8 57.9 1.0
OE1 A:GLN354 4.9 57.9 1.0
NE2 A:GLN354 5.0 57.9 1.0
N A:GLY139 5.0 57.0 1.0

Bromine binding site 2 out of 6 in 8kg5

Go back to Bromine Binding Sites List in 8kg5
Bromine binding site 2 out of 6 in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Prefusion Rsv F Bound to Lonafarnib and D25 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br601

b:94.7
occ:1.00
 BR38 A:336601 0.0 94.7 1.0
C28 A:336601 1.9 94.7 1.0
C35 A:336601 2.8 94.7 1.0
C40 A:336601 3.1 94.7 1.0
C4 A:336601 3.2 94.7 1.0
CD1 A:PHE137 3.2 63.0 1.0
C6 A:336601 3.5 94.7 1.0
C33 A:336601 3.6 94.7 1.0
CA A:PHE137 3.6 63.0 1.0
CE1 A:PHE137 3.9 63.0 1.0
CG A:PHE137 4.0 63.0 1.0
C19 A:336601 4.1 94.7 1.0
CB A:PHE137 4.2 63.0 1.0
N A:PHE137 4.2 63.0 1.0
C42 A:336601 4.3 94.7 1.0
C13 A:336601 4.4 94.7 1.0
O A:PHE137 4.6 63.0 1.0
C A:PHE137 4.6 63.0 1.0
C1 A:336601 4.7 94.7 1.0
C20 A:336601 4.7 94.7 1.0
C39 A:336601 4.7 94.7 1.0
CB C:PHE140 4.7 58.7 1.0
CA C:PHE140 4.8 58.7 1.0
C9 A:336601 4.9 94.7 1.0
CZ A:PHE137 5.0 63.0 1.0
BR37 C:336601 5.0 93.7 1.0

Bromine binding site 3 out of 6 in 8kg5

Go back to Bromine Binding Sites List in 8kg5
Bromine binding site 3 out of 6 in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Prefusion Rsv F Bound to Lonafarnib and D25 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Br601

b:93.1
occ:1.00
 BR37 B:336601 0.0 93.1 1.0
C29 B:336601 1.9 93.1 1.0
C17 B:336601 2.9 93.1 1.0
C30 B:336601 2.9 93.1 1.0
O B:GLY139 3.0 58.3 1.0
C B:GLY139 3.3 58.3 1.0
CA B:GLY139 3.7 58.3 1.0
N B:PHE140 4.0 59.5 1.0
C41 B:336601 4.2 93.1 1.0
N32 B:336601 4.2 93.1 1.0
C35 C:336601 4.3 93.7 1.0
C19 C:336601 4.3 93.7 1.0
C28 C:336601 4.4 93.7 1.0
C20 C:336601 4.4 93.7 1.0
C42 C:336601 4.5 93.7 1.0
C40 C:336601 4.5 93.7 1.0
CD B:GLN354 4.6 62.3 1.0
CA B:PHE140 4.6 59.5 1.0
C39 B:336601 4.7 93.1 1.0
C6 C:336601 4.7 93.7 1.0
CG B:GLN354 4.7 62.3 1.0
OE1 B:GLN354 4.8 62.3 1.0
NE2 B:GLN354 4.8 62.3 1.0
N B:GLY139 4.9 58.3 1.0

Bromine binding site 4 out of 6 in 8kg5

Go back to Bromine Binding Sites List in 8kg5
Bromine binding site 4 out of 6 in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Prefusion Rsv F Bound to Lonafarnib and D25 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Br601

b:93.1
occ:1.00
 BR38 B:336601 0.0 93.1 1.0
C28 B:336601 1.9 93.1 1.0
C35 B:336601 2.8 93.1 1.0
C40 B:336601 3.1 93.1 1.0
CD1 B:PHE137 3.2 65.1 1.0
C4 B:336601 3.2 93.1 1.0
C6 B:336601 3.5 93.1 1.0
C33 B:336601 3.6 93.1 1.0
CA B:PHE137 3.7 65.1 1.0
CE1 B:PHE137 3.8 65.1 1.0
CG B:PHE137 4.0 65.1 1.0
C19 B:336601 4.1 93.1 1.0
CB B:PHE137 4.2 65.1 1.0
N B:PHE137 4.3 65.1 1.0
C42 B:336601 4.3 93.1 1.0
C13 B:336601 4.4 93.1 1.0
C B:PHE137 4.7 65.1 1.0
C1 B:336601 4.7 93.1 1.0
O B:PHE137 4.7 65.1 1.0
C20 B:336601 4.7 93.1 1.0
C39 B:336601 4.7 93.1 1.0
CB A:PHE140 4.7 56.9 1.0
CA A:PHE140 4.8 56.9 1.0
C9 B:336601 4.9 93.1 1.0
CZ B:PHE137 4.9 65.1 1.0

Bromine binding site 5 out of 6 in 8kg5

Go back to Bromine Binding Sites List in 8kg5
Bromine binding site 5 out of 6 in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Prefusion Rsv F Bound to Lonafarnib and D25 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Br601

b:93.7
occ:1.00
 BR37 C:336601 0.0 93.7 1.0
C29 C:336601 1.9 93.7 1.0
O C:GLY139 2.8 57.2 1.0
C17 C:336601 2.9 93.7 1.0
C30 C:336601 2.9 93.7 1.0
C C:GLY139 3.1 57.2 1.0
CA C:GLY139 3.6 57.2 1.0
N C:PHE140 3.8 58.7 1.0
C35 A:336601 4.1 94.7 1.0
C28 A:336601 4.2 94.7 1.0
C41 C:336601 4.2 93.7 1.0
N32 C:336601 4.2 93.7 1.0
C19 A:336601 4.2 94.7 1.0
C40 A:336601 4.4 94.7 1.0
CA C:PHE140 4.4 58.7 1.0
C20 A:336601 4.4 94.7 1.0
C42 A:336601 4.5 94.7 1.0
C6 A:336601 4.5 94.7 1.0
C39 C:336601 4.7 93.7 1.0
CD C:GLN354 4.8 58.8 1.0
N C:GLY139 4.9 57.2 1.0
CG C:GLN354 4.9 58.8 1.0
BR38 A:336601 5.0 94.7 1.0

Bromine binding site 6 out of 6 in 8kg5

Go back to Bromine Binding Sites List in 8kg5
Bromine binding site 6 out of 6 in the Prefusion Rsv F Bound to Lonafarnib and D25 Fab


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 6 of Prefusion Rsv F Bound to Lonafarnib and D25 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Br601

b:93.7
occ:1.00
 BR38 C:336601 0.0 93.7 1.0
C28 C:336601 1.9 93.7 1.0
C35 C:336601 2.8 93.7 1.0
C40 C:336601 3.1 93.7 1.0
CD1 C:PHE137 3.1 60.4 1.0
C4 C:336601 3.2 93.7 1.0
C6 C:336601 3.5 93.7 1.0
CA C:PHE137 3.5 60.4 1.0
C33 C:336601 3.6 93.7 1.0
CE1 C:PHE137 3.7 60.4 1.0
CG C:PHE137 3.8 60.4 1.0
CB C:PHE137 4.0 60.4 1.0
N C:PHE137 4.1 60.4 1.0
C19 C:336601 4.1 93.7 1.0
C42 C:336601 4.3 93.7 1.0
C13 C:336601 4.4 93.7 1.0
O C:PHE137 4.5 60.4 1.0
C C:PHE137 4.5 60.4 1.0
C1 C:336601 4.7 93.7 1.0
C20 C:336601 4.7 93.7 1.0
C39 C:336601 4.7 93.7 1.0
CB B:PHE140 4.8 59.5 1.0
CZ C:PHE137 4.8 60.4 1.0
CA B:PHE140 4.9 59.5 1.0
C9 C:336601 4.9 93.7 1.0
CD2 C:PHE137 4.9 60.4 1.0

Reference:

Q.Yang, B.Xue, F.Liu, Y.Lu, J.Tang, M.Yan, Q.Wu, R.Chen, A.Zhou, L.Liu, J.Liu, C.Qu, Q.Wu, M.Fu, J.Zhong, J.Dong, S.Chen, F.Wang, Y.Zhou, J.Zheng, W.Peng, J.Shang, X.Chen. Farnesyltransferase Inhibitor Lonafarnib Suppresses Respiratory Syncytial Virus Infection By Blocking Conformational Change of Fusion Glycoprotein. Signal Transduct Target Ther V. 9 144 2024.
ISSN: ESSN 2059-3635
PubMed: 38853183
DOI: 10.1038/S41392-024-01858-5
Page generated: Thu Jul 11 05:24:58 2024

Last articles

Mg in 4Y52
Mg in 4Y30
Mg in 4Y2V
Mg in 4Y2X
Mg in 4Y2Y
Mg in 4Y2U
Mg in 4Y2T
Mg in 4Y2Q
Mg in 4Y2R
Mg in 4Y2S
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy