Bromine »
PDB 8pot-8u2v »
8qcd »
Bromine in PDB 8qcd: Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
Enzymatic activity of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
All present enzymatic activity of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole:
2.7.11.1;
2.7.11.1;
Protein crystallography data
The structure of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole, PDB code: 8qcd
was solved by
C.Werner,
K.Niefind,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 24.92 / 1.03 |
| Space group | P 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 46.338, 47.701, 50.342, 113.48, 90.45, 90.17 |
| R / Rfree (%) | 14.4 / 15.6 |
Bromine Binding Sites:
The binding sites of Bromine atom in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
(pdb code 8qcd). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole, PDB code: 8qcd:
Jump to Bromine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Bromine where determined in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole, PDB code: 8qcd:
Jump to Bromine binding site number: 1; 2; 3; 4;
Bromine binding site 1 out of 4 in 8qcd
Go back to
Bromine Binding Sites List in 8qcd
Bromine binding site 1 out
of 4 in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole within 5.0Å range:
|
Bromine binding site 2 out of 4 in 8qcd
Go back to
Bromine Binding Sites List in 8qcd
Bromine binding site 2 out
of 4 in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole within 5.0Å range:
|
Bromine binding site 3 out of 4 in 8qcd
Go back to
Bromine Binding Sites List in 8qcd
Bromine binding site 3 out
of 4 in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 3 of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole within 5.0Å range:
|
Bromine binding site 4 out of 4 in 8qcd
Go back to
Bromine Binding Sites List in 8qcd
Bromine binding site 4 out
of 4 in the Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 4 of Structure of Protein Kinase CK2 Catalytic Subunit (Isoform CK2ALPHA'; CSNK2A2 Gene Product) in Complex with the Inhibitor 4,5,6,7- Tetrabromobenzotriazole within 5.0Å range:
|
Reference:
C.Werner,
D.Lindenblatt,
K.Viht,
A.Uri,
K.Niefind.
Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2ALPHA CYS336SER As An Exquisite Crystallographic Tool Kinases Phosphatases 2023.
DOI: 10.3390/KINASESPHOSPHATASES1040018
Page generated: Thu Jul 11 05:30:01 2024
DOI: 10.3390/KINASESPHOSPHATASES1040018
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
