Bromine in PDB 8wc9: Cryo-Em Structure of the ZH8651-Bound MTAAR1-Gq Complex

The binding sites of Bromine atom in the Cryo-Em Structure of the ZH8651-Bound MTAAR1-Gq Complex (pdb code 8wc9). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Cryo-Em Structure of the ZH8651-Bound MTAAR1-Gq Complex, PDB code: 8wc9:

Bromine binding site 1 out of 1 in the Cryo-Em Structure of the ZH8651-Bound MTAAR1-Gq Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Cryo-Em Structure of the ZH8651-Bound MTAAR1-Gq Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:Br401 b:104.3 occ:1.00 BR01 R:VMT401 0.0 104.3 1.0 C01 R:VMT401 1.9 104.3 1.0 C06 R:VMT401 2.9 104.3 1.0 C02 R:VMT401 2.9 104.3 1.0 CB R:ALA193 3.7 91.0 1.0 CE1 R:PHE265 3.8 93.2 1.0 CZ R:PHE265 4.0 93.2 1.0 OH R:TYR153 4.0 95.5 1.0 C05 R:VMT401 4.2 104.3 1.0 C03 R:VMT401 4.2 104.3 1.0 O R:ALA193 4.5 91.0 1.0 CA R:ALA193 4.5 91.0 1.0 C R:ALA193 4.5 91.0 1.0 CB R:SER197 4.6 76.6 1.0 OG R:SER197 4.6 76.6 1.0 CG2 R:ILE103 4.7 74.7 1.0 C04 R:VMT401 4.7 104.3 1.0 CD1 R:ILE103 4.8 74.7 1.0 CZ R:PHE185 4.8 109.5 1.0 CE2 R:TYR153 4.9 95.5 1.0 CD1 R:PHE265 4.9 93.2 1.0 CZ R:TYR153 5.0 95.5 1.0 CG1 R:ILE103 5.0 74.7 1.0

P.Shang, N.Rong, J.J.Jiang, J.Cheng, M.H.Zhang, D.Kang, L.Qi, L.Guo, G.M.Yang, Q.Liu, Z.Zhou, X.B.Li, K.K.Zhu, Q.B.Meng, X.Han, W.Yan, Y.Kong, L.Yang, X.Wang, D.Lei, X.Feng, X.Liu, X.Yu, Y.Wang, Q.Li, Z.H.Shao, F.Yang, J.P.Sun. Structural and Signaling Mechanisms of TAAR1 Enabled Preferential Agonist Design. Cell V. 186 5347 2023.
ISSN: ISSN 1097-4172
PubMed: 37963465
DOI: 10.1016/J.CELL.2023.10.014