Atomistry » Bromine » PDB 2qc6-2vo5 » 2r4g
Atomistry »
  Bromine »
    PDB 2qc6-2vo5 »
      2r4g »

Bromine in PDB 2r4g: The High Resolution Structure of the Rna-Binding Domain of Telomerase

Enzymatic activity of The High Resolution Structure of the Rna-Binding Domain of Telomerase

All present enzymatic activity of The High Resolution Structure of the Rna-Binding Domain of Telomerase:
2.7.7.49;

Protein crystallography data

The structure of The High Resolution Structure of the Rna-Binding Domain of Telomerase, PDB code: 2r4g was solved by S.Rouda, E.Skordalakes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.71
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 39.354, 67.220, 51.533, 90.00, 90.66, 90.00
R / Rfree (%) 20 / 23.9

Bromine Binding Sites:

The binding sites of Bromine atom in the The High Resolution Structure of the Rna-Binding Domain of Telomerase (pdb code 2r4g). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 7 binding sites of Bromine where determined in the The High Resolution Structure of the Rna-Binding Domain of Telomerase, PDB code: 2r4g:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6; 7;

Bromine binding site 1 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 1 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br1

b:28.1
occ:1.00
 NH1 A:ARG492 3.5 18.7 1.0
N A:LEU333 3.5 19.2 1.0
O A:HOH567 3.7 36.5 1.0
CG A:LYS328 3.8 19.0 1.0
CA A:LYS328 3.8 17.9 1.0
CG A:LEU333 3.8 20.3 1.0
CD1 A:LEU333 3.9 20.2 1.0
CB A:LEU333 4.0 20.1 1.0
CB A:LYS328 4.0 17.9 1.0
CG A:LYS332 4.0 20.6 1.0
CA A:LYS332 4.1 17.9 1.0
NH2 A:ARG492 4.2 18.1 1.0
CZ A:ARG492 4.3 17.5 1.0
C A:LYS332 4.3 18.3 1.0
CA A:LEU333 4.4 20.3 1.0
N A:LYS328 4.4 16.6 1.0
CD A:LYS328 4.5 19.5 1.0
O A:HOH724 4.6 40.7 1.0
CB A:LYS332 4.7 18.1 1.0
O A:LEU327 4.7 16.0 1.0
O A:HOH722 4.8 36.3 1.0
C A:LEU327 4.8 16.1 1.0
C A:LYS328 4.9 17.9 1.0
O A:LYS328 4.9 18.5 1.0
CE A:LYS328 5.0 21.5 1.0

Bromine binding site 2 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 2 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br2

b:45.8
occ:1.00
 CA A:GLU407 3.8 17.0 1.0
CD2 A:TYR406 3.8 20.3 1.0
CB A:GLU407 3.9 16.8 1.0
CD A:GLN410 3.9 21.6 1.0
CG A:GLN410 4.0 19.4 1.0
CE2 A:TYR406 4.0 20.8 1.0
CG A:GLU407 4.0 19.5 1.0
NE2 A:GLN410 4.0 21.0 1.0
OE1 A:GLN410 4.2 21.7 1.0
N A:GLU407 4.3 16.2 1.0
O A:HOH534 4.8 20.1 1.0
CD A:GLU407 4.9 19.4 1.0
C A:TYR406 4.9 16.4 1.0
OE2 A:GLU407 5.0 25.2 1.0

Bromine binding site 3 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 3 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br3

b:59.4
occ:1.00
 N A:VAL428 3.2 17.8 1.0
O A:HOH641 3.4 39.6 1.0
CA A:ASP427 3.6 18.4 1.0
CG2 A:ILE449 3.7 17.4 1.0
CG2 A:VAL428 3.8 18.4 1.0
OD1 A:ASP427 3.9 21.5 1.0
O A:MET426 3.9 18.6 1.0
C A:ASP427 3.9 17.9 1.0
NE A:ARG453 4.0 28.8 1.0
CG1 A:ILE449 4.1 17.1 1.0
CG1 A:VAL428 4.1 18.6 1.0
O A:HOH681 4.2 55.3 1.0
CB A:VAL428 4.2 17.8 1.0
CA A:VAL428 4.3 17.6 1.0
N A:ASP427 4.5 18.1 1.0
CD1 A:ILE449 4.5 16.7 1.0
CB A:ILE449 4.5 16.6 1.0
CG A:ASP427 4.6 20.7 1.0
C A:MET426 4.6 18.7 1.0
NH2 A:ARG453 4.6 32.6 1.0
CG A:ARG453 4.6 19.5 1.0
CB A:ASP427 4.6 18.7 1.0
CZ A:ARG453 4.8 30.8 1.0
CD A:ARG453 4.8 21.3 1.0

Bromine binding site 4 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 4 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br4

b:49.1
occ:1.00
 CG A:LYS447 3.7 19.0 1.0
CB A:ARG446 3.8 20.7 1.0
C A:GLN444 3.8 22.4 1.0
CA A:GLN444 3.8 22.4 1.0
N A:ARG446 3.9 21.2 1.0
CB A:GLN444 3.9 22.5 1.0
O A:GLN444 3.9 22.0 1.0
CE A:LYS447 4.0 21.2 1.0
N A:LYS447 4.0 18.8 1.0
NE A:ARG446 4.2 26.6 1.0
CA A:ARG446 4.3 20.3 1.0
CD A:LYS447 4.3 20.3 1.0
N A:LYS445 4.3 22.5 1.0
CG A:GLN444 4.5 24.7 1.0
NH2 A:ARG446 4.5 27.8 1.0
CG A:ARG446 4.6 22.1 1.0
C A:ARG446 4.6 19.6 1.0
CB A:LYS447 4.7 18.7 1.0
CZ A:ARG446 4.7 27.9 1.0
C A:LYS445 4.8 22.0 1.0
CA A:LYS447 5.0 18.4 1.0
CD A:ARG446 5.0 24.1 1.0

Bromine binding site 5 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 5 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br5

b:46.3
occ:1.00
 O A:HOH571 3.2 24.3 1.0
CB A:GLN391 3.8 17.0 1.0
CZ A:PHE310 3.9 17.5 1.0
CB A:GLU432 4.0 17.4 1.0
CB A:TRP433 4.0 15.4 1.0
OE1 A:GLU432 4.0 23.9 1.0
CD1 A:TRP433 4.0 15.3 1.0
O A:HOH521 4.2 16.8 1.0
CG A:GLN391 4.2 17.8 1.0
CG A:TRP433 4.4 15.4 1.0
N A:TRP433 4.4 16.0 1.0
CD A:GLN391 4.4 21.3 1.0
OE1 A:GLN391 4.5 21.9 1.0
O A:GLN391 4.6 15.6 1.0
C A:GLU432 4.6 16.7 1.0
CA A:TRP433 4.7 15.9 1.0
CE1 A:PHE310 4.7 18.1 1.0
CD A:GLU432 4.8 19.8 1.0
CE2 A:PHE310 4.8 16.6 1.0
CA A:GLU432 4.8 17.5 1.0
CG A:GLU432 5.0 19.9 1.0
CA A:GLN391 5.0 16.1 1.0

Bromine binding site 6 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 6 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 6 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br6

b:42.5
occ:1.00
 NH1 A:ARG473 3.5 30.7 1.0
O A:HOH625 3.5 30.9 1.0
O A:HOH684 3.5 30.5 1.0
O A:HOH554 3.5 25.1 1.0
CG A:PRO470 3.8 14.4 1.0
CD1 A:ILE284 4.1 16.5 1.0
CA A:PRO470 4.1 14.6 1.0
CD A:ARG473 4.2 23.1 1.0
CD A:PRO470 4.2 14.7 1.0
N A:PRO470 4.2 14.4 1.0
CB A:PRO470 4.3 15.2 1.0
CG2 A:ILE469 4.3 15.6 1.0
CZ A:ARG473 4.4 29.4 1.0
O A:HOH678 4.5 35.1 1.0
NE A:ARG473 4.7 27.0 1.0
O A:HOH541 4.7 19.8 1.0
CG2 A:ILE284 4.8 15.5 1.0
C A:ILE469 4.8 14.8 1.0
CG1 A:ILE284 4.9 15.6 1.0
O A:ASN465 5.0 15.5 1.0

Bromine binding site 7 out of 7 in 2r4g

Go back to Bromine Binding Sites List in 2r4g
Bromine binding site 7 out of 7 in the The High Resolution Structure of the Rna-Binding Domain of Telomerase


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 7 of The High Resolution Structure of the Rna-Binding Domain of Telomerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br7

b:28.4
occ:1.00
 N A:GLN294 3.3 18.6 1.0
O A:HOH559 3.7 27.9 1.0
NE A:ARG304 3.8 28.0 1.0
CA A:TYR293 4.0 19.1 1.0
CE2 A:PHE307 4.0 16.8 1.0
C A:TYR293 4.1 19.0 1.0
CB A:GLN294 4.2 18.7 1.0
CA A:GLN294 4.2 18.9 1.0
CE2 A:PHE298 4.2 19.3 1.0
CD2 A:PHE307 4.2 16.7 1.0
CG A:GLN294 4.2 20.1 1.0
NH2 A:ARG304 4.3 32.3 1.0
CZ A:ARG304 4.3 30.3 1.0
CD1 A:TYR293 4.3 21.6 1.0
CB A:TYR293 4.4 19.9 1.0
CD2 A:LEU308 4.4 18.4 1.0
N A:SER295 4.4 18.4 1.0
CD A:ARG304 4.5 19.2 1.0
CG A:ARG304 4.5 18.8 1.0
C A:GLN294 4.8 18.8 1.0
CG A:TYR293 4.8 21.1 1.0
O A:GLU292 4.9 18.1 1.0
CD2 A:PHE298 5.0 17.7 1.0
O A:SER295 5.0 18.4 1.0

Reference:

S.Rouda, E.Skordalakes. Structure of the Rna-Binding Domain of Telomerase: Implications For Rna Recognition and Binding. Structure V. 15 1403 2007.
ISSN: ISSN 0969-2126
PubMed: 17997966
DOI: 10.1016/J.STR.2007.09.007
Page generated: Mon Jul 7 04:39:09 2025

Last articles

K in 8CGJ
K in 8CGI
K in 8CG1
K in 8CFY
K in 8CG2
K in 8CFX
K in 8CG0
K in 8CFW
K in 8CFV
K in 8CFU
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy