Bromine in PDB 3po3: Arrested Rna Polymerase II Reactivation Intermediate

All present enzymatic activity of Arrested Rna Polymerase II Reactivation Intermediate:
2.7.7.6;

The structure of Arrested Rna Polymerase II Reactivation Intermediate, PDB code: 3po3 was solved by A.C.M.Cheung, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.97 / 3.30
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	220.019, 395.067, 280.429, 90.00, 90.00, 90.00
R / Rfree (%)	16.1 / 18.9

The structure of Arrested Rna Polymerase II Reactivation Intermediate also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	9 atoms

The binding sites of Bromine atom in the Arrested Rna Polymerase II Reactivation Intermediate (pdb code 3po3). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Arrested Rna Polymerase II Reactivation Intermediate, PDB code: 3po3:

Bromine binding site 1 out of 1 in the Arrested Rna Polymerase II Reactivation Intermediate


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Arrested Rna Polymerase II Reactivation Intermediate within 5.0Å range: probe atom residue distance (Å) B Occ T:Br22 b:0.1 occ:1.00 BR T:BRU22 0.0 0.1 1.0 C5 T:BRU22 1.9 0.7 1.0 C6 T:BRU22 2.8 0.6 1.0 C4 T:BRU22 2.9 0.9 1.0 O4 T:BRU22 3.1 0.1 1.0 OE2 B:GLU1120 3.2 0.3 1.0 C4 T:DG21 3.8 0.7 1.0 N9 T:DG21 3.8 0.5 1.0 C5 T:DG21 3.8 0.5 1.0 C8 T:DG21 3.9 0.5 1.0 C2' T:DG21 4.0 0.4 1.0 N7 T:DG21 4.0 0.7 1.0 N1 T:BRU22 4.1 0.5 1.0 N3 T:BRU22 4.2 0.2 1.0 N3 T:DG21 4.3 0.8 1.0 CD B:GLU1120 4.3 0.6 1.0 C3' T:DG21 4.4 0.8 1.0 C1' T:DG21 4.4 0.0 1.0 C6 T:DG21 4.5 0.9 1.0 C2 T:BRU22 4.7 0.1 1.0 CG B:GLU1120 4.7 0.2 1.0 C2 T:DG21 4.8 0.4 1.0 N1 T:DG21 4.8 0.1 1.0

A.C.Cheung, P.Cramer. Structural Basis of Rna Polymerase II Backtracking, Arrest and Reactivation. Nature V. 471 249 2011.
ISSN: ISSN 0028-0836
PubMed: 21346759
DOI: 10.1038/NATURE09785