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Bromine in PDB 4m47: Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp
Enzymatic activity of Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp
All present enzymatic activity of Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp, PDB code: 4m47
was solved by
M.C.Koag,
K.Min,
A.F.Monzingo,
S.Lee,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 19.82 / 2.37 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 55.175, 79.267, 55.294, 90.00, 107.80, 90.00 |
| R / Rfree (%) | 20.9 / 27.3 |
Other elements in 4m47:
The structure of Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
| Sodium | (Na) | 3 atoms |
Bromine Binding Sites:
The binding sites of Bromine atom in the Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp
(pdb code 4m47). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp, PDB code: 4m47:
In total only one binding site of Bromine was determined in the Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp, PDB code: 4m47:
Bromine binding site 1 out of 1 in 4m47
Go back to
Bromine Binding Sites List in 4m47
Bromine binding site 1 out
of 1 in the Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Structure of Human Dna Polymerase Complexed with 8-Brg in the Template Base Paired with Incoming Non-Hydrolyzable Gtp within 5.0Å range:
|
Reference:
M.C.Koag,
K.Min,
S.Lee.
Structural Basis For Promutagenicity of 8-Halogenated Guanine. J.Biol.Chem. V. 289 6289 2014.
ISSN: ISSN 0021-9258
PubMed: 24425881
DOI: 10.1074/JBC.M113.537803
Page generated: Wed Jul 10 22:01:32 2024
ISSN: ISSN 0021-9258
PubMed: 24425881
DOI: 10.1074/JBC.M113.537803
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