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Atomistry » Bromine » PDB 4x6i-4z8b » 4x8s | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 4x6i-4z8b » 4x8s » |
Bromine in PDB 4x8s: Factor Viia in Complex with the Inhibitor 4-Bromo-2-MethoxyphenolEnzymatic activity of Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol
All present enzymatic activity of Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol:
3.4.21.21; Protein crystallography data
The structure of Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol, PDB code: 4x8s
was solved by
A.Wei,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4x8s:
The structure of Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol
(pdb code 4x8s). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol, PDB code: 4x8s: Bromine binding site 1 out of 1 in 4x8sGo back to![]() ![]()
Bromine binding site 1 out
of 1 in the Factor Viia in Complex with the Inhibitor 4-Bromo-2-Methoxyphenol
![]() Mono view ![]() Stereo pair view
Reference:
D.L.Cheney,
J.M.Bozarth,
W.J.Metzler,
P.E.Morin,
L.Mueller,
J.A.Newitt,
A.H.Nirschl,
A.R.Rendina,
J.K.Tamura,
A.Wei,
X.Wen,
N.R.Wurtz,
D.A.Seiffert,
R.R.Wexler,
E.S.Priestley.
Discovery of Novel P1 Groups For Coagulation Factor Viia Inhibition Using Fragment-Based Screening. J.Med.Chem. 2015.
Page generated: Wed Jul 10 23:01:27 2024
ISSN: ISSN 0022-2623 PubMed: 25764119 DOI: 10.1021/JM501982K |
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