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Atomistry » Bromine » PDB 5cc3-5ev2 » 5dr9 » |
Bromine in PDB 5dr9: Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122Enzymatic activity of Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122
All present enzymatic activity of Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122:
2.7.11.1; Protein crystallography data
The structure of Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122, PDB code: 5dr9
was solved by
M.Janecek,
M.Rossmann,
P.Sharma,
A.Emery,
G.J.Mckenzie,
D.J.Huggins,
S.Stockwell,
J.A.Stokes,
E.G.Almeida,
B.Hardwick,
A.J.Narvaez,
M.Hyvonen,
D.R.Spring,
A.R.Venkitaraman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5dr9:
The structure of Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122 also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122
(pdb code 5dr9). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122, PDB code: 5dr9: Bromine binding site 1 out of 1 in 5dr9Go back to![]() ![]()
Bromine binding site 1 out
of 1 in the Aurora A Kinase in Complex with AA29 and Jnj-7706621 in Space Group P6122
![]() Mono view ![]() Stereo pair view
Reference:
M.Janecek,
M.Rossmann,
P.Sharma,
A.Emery,
D.J.Huggins,
S.R.Stockwell,
J.E.Stokes,
Y.S.Tan,
E.G.Almeida,
B.Hardwick,
A.J.Narvaez,
M.Hyvonen,
D.R.Spring,
G.J.Mckenzie,
A.R.Venkitaraman.
Allosteric Modulation of Aurka Kinase Activity By A Small-Molecule Inhibitor of Its Protein-Protein Interaction with TPX2. Sci Rep V. 6 28528 2016.
Page generated: Wed Jul 10 23:27:07 2024
ISSN: ESSN 2045-2322 PubMed: 27339427 DOI: 10.1038/SREP28528 |
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