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Bromine in PDB 6cr3: Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue
Enzymatic activity of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue
All present enzymatic activity of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue, PDB code: 6cr3
was solved by
V.K.Batra,
S.H.Wilson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 23.18 / 1.95 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 50.874, 79.669, 55.784, 90.00, 107.72, 90.00 |
| R / Rfree (%) | 17.5 / 22.7 |
Other elements in 6cr3:
The structure of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
| Chlorine | (Cl) | 2 atoms |
| Sodium | (Na) | 3 atoms |
Bromine Binding Sites:
The binding sites of Bromine atom in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue
(pdb code 6cr3). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue, PDB code: 6cr3:
Jump to Bromine binding site number: 1; 2;
In total 2 binding sites of Bromine where determined in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue, PDB code: 6cr3:
Jump to Bromine binding site number: 1; 2;
Bromine binding site 1 out of 2 in 6cr3
Go back to
Bromine Binding Sites List in 6cr3
Bromine binding site 1 out
of 2 in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue within 5.0Å range:
|
Bromine binding site 2 out of 2 in 6cr3
Go back to
Bromine Binding Sites List in 6cr3
Bromine binding site 2 out
of 2 in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Datp Analogue within 5.0Å range:
|
Reference:
V.K.Batra,
K.Oertell,
W.A.Beard,
B.A.Kashemirov,
C.E.Mckenna,
M.F.Goodman,
S.H.Wilson.
Mapping Functional Substrate-Enzyme Interactions in the Pol Beta Active Site Through Chemical Biology: Structural Responses to Acidity Modification of Incoming Dntps. Biochemistry V. 57 3934 2018.
ISSN: ISSN 1520-4995
PubMed: 29874056
DOI: 10.1021/ACS.BIOCHEM.8B00418
Page generated: Mon Jul 7 09:36:33 2025
ISSN: ISSN 1520-4995
PubMed: 29874056
DOI: 10.1021/ACS.BIOCHEM.8B00418
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