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Atomistry » Bromine » PDB 6e4l-6h45 » 6f86 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 6e4l-6h45 » 6f86 » |
Bromine in PDB 6f86: Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-CarboxamideEnzymatic activity of Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-Carboxamide
All present enzymatic activity of Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-Carboxamide:
5.99.1.3; Protein crystallography data
The structure of Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-Carboxamide, PDB code: 6f86
was solved by
S.K.Narramore,
C.E.M.Stevenson,
D.M.Lawson,
A.Maxwell,
C.W.G.Fishwick,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-Carboxamide
(pdb code 6f86). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-Carboxamide, PDB code: 6f86: Bromine binding site 1 out of 1 in 6f86Go back to![]() ![]()
Bromine binding site 1 out
of 1 in the Crystal Structure of E. Coli Gyraseb 24KDA in Complex with 4-(4-Bromo- 1H-Pyrazol-1-Yl)-6-[(Ethylcarbamoyl)Amino]-N-(Pyridin-3-Yl)Pyridine- 3-Carboxamide
![]() Mono view ![]() Stereo pair view
Reference:
S.Narramore,
C.E.M.Stevenson,
A.Maxwell,
D.M.Lawson,
C.W.G.Fishwick.
New Insights Into the Binding Mode of Pyridine-3-Carboxamide Inhibitors of E. Coli Dna Gyrase. Bioorg.Med.Chem. V. 27 3546 2019.
Page generated: Thu Jul 11 01:53:38 2024
ISSN: ESSN 1464-3391 PubMed: 31257079 DOI: 10.1016/J.BMC.2019.06.015 |
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