Bromine in PDB 6h42: Crystal Structure of the Human Tgt Catalytic Subunit QTRT1

All present enzymatic activity of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1:
2.4.2.29;

The structure of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1, PDB code: 6h42 was solved by S.Johannsson, P.Neumann, R.Ficner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.25 / 2.45
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	127.700, 157.820, 47.770, 90.00, 108.46, 90.00
R / Rfree (%)	20.2 / 23.1

The structure of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 also contains other interesting chemical elements:

Potassium	(K)	2 atoms
Zinc	(Zn)	2 atoms
Chlorine	(Cl)	10 atoms

The binding sites of Bromine atom in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 (pdb code 6h42). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1, PDB code: 6h42:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br508 b:0.9 occ:0.76 OD1 A:ASN196 3.7 51.5 1.0 CG2 A:ILE16 4.2 55.3 1.0 O A:PRO192 4.2 72.5 1.0 CG A:ASN196 4.6 49.7 1.0 O A:ASP193 4.8 67.9 1.0 ND2 A:ASN196 4.8 48.5 1.0

Bromine binding site 2 out of 2 in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Br508 b:0.8 occ:0.50 N B:GLU123 3.4 88.9 1.0 CB B:GLU123 3.5 87.5 1.0 OG1 B:THR121 3.9 91.3 1.0 CA B:GLU123 4.1 87.5 1.0 N B:GLU122 4.2 90.8 1.0 CB B:GLU122 4.3 91.0 1.0 CB B:THR121 4.3 92.2 1.0 C B:GLU122 4.3 90.0 1.0 OE2 B:GLU123 4.4 91.9 1.0 CA B:GLU122 4.5 90.5 1.0 O B:HOH601 4.5 0.2 0.5 NH2 B:ARG126 4.6 0.4 1.0 CG B:GLU123 4.7 87.5 1.0 CD B:GLU123 4.9 90.7 1.0 C B:THR121 5.0 90.9 1.0

S.Johannsson, P.Neumann, R.Ficner. Crystal Structure of the Human Trna Guanine Transglycosylase Catalytic Subunit QTRT1. Biomolecules V. 8 2018.
ISSN: ISSN 2218-273X
PubMed: 30149595
DOI: 10.3390/BIOM8030081