Bromine in PDB 6mn8: Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide

The structure of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide, PDB code: 6mn8 was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.28 / 2.35
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	159.720, 159.720, 143.720, 90.00, 90.00, 120.00
R / Rfree (%)	14.2 / 18

The structure of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Chlorine	(Cl)	1 atom

The binding sites of Bromine atom in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide (pdb code 6mn8). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide, PDB code: 6mn8:

Bromine binding site 1 out of 1 in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide within 5.0Å range: probe atom residue distance (Å) B Occ A:Br603 b:70.7 occ:1.00 BR1 A:HFG603 0.0 70.7 1.0 C7 A:HFG603 1.9 43.8 1.0 C8 A:HFG603 2.8 31.0 1.0 C6 A:HFG603 2.9 31.6 1.0 CL1 A:HFG603 3.3 39.5 1.0 O A:PHE135 3.3 90.7 1.0 CB A:GLU138 3.5 47.5 1.0 CB A:PRO158 3.6 23.0 1.0 CG2 A:VAL139 3.6 45.4 1.0 O A:GLU138 3.8 40.9 1.0 CG A:PRO158 3.8 20.9 1.0 C A:GLU138 3.9 36.8 1.0 C A:PHE135 4.1 0.0 1.0 C9 A:HFG603 4.1 28.8 1.0 C5 A:HFG603 4.2 29.1 1.0 CA A:GLU138 4.2 51.5 1.0 OE1 A:GLU138 4.2 45.0 1.0 CB A:PHE135 4.3 93.1 1.0 N A:VAL139 4.4 32.7 1.0 CA A:PHE135 4.6 0.3 1.0 N A:GLU138 4.6 60.1 1.0 C10 A:HFG603 4.6 32.7 1.0 CG A:GLU138 4.7 63.7 1.0 CA A:VAL139 4.7 34.2 1.0 CG A:PHE135 4.8 85.4 1.0 CB A:VAL139 4.8 41.2 1.0 CD A:GLU138 4.9 64.8 1.0 CG A:ARG190 4.9 24.3 1.0 CD1 A:PHE135 4.9 83.4 1.0

D.M.Dranow, D.G.Conrady, D.D.Lorimer, P.S.Horanyi, T.E.Edwards. Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide To Be Published.