Atomistry » Bromine » PDB 6w0s-6yoc » 6wad
Atomistry »
  Bromine »
    PDB 6w0s-6yoc »
      6wad »

Bromine in PDB 6wad: Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor

Enzymatic activity of Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor

All present enzymatic activity of Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor:
2.1.1.319;

Protein crystallography data

The structure of Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor, PDB code: 6wad was solved by L.Halabelian, H.Zeng, A.Dong, M.Schapira, R.F.De Freitas, A.Hutchinson, A.Seitova, C.Bountra, A.M.Edwards, C.H.Arrowsmith, P.J.Brown, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.08 / 2.45
Space group I 41
Cell size a, b, c (Å), α, β, γ (°) 94.068, 94.068, 109.242, 90.00, 90.00, 90.00
R / Rfree (%) 19.3 / 22.6

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor (pdb code 6wad). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor, PDB code: 6wad:

Bromine binding site 1 out of 1 in 6wad

Go back to Bromine Binding Sites List in 6wad
Bromine binding site 1 out of 1 in the Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br502

b:0.1
occ:1.00
BR A:TQ7502 0.0 0.1 1.0
C5 A:TQ7502 1.9 80.1 1.0
C4 A:TQ7502 2.9 68.1 1.0
S A:TQ7502 3.1 69.7 1.0
CG2 A:ILE290 3.9 40.5 1.0
CD1 A:ILE290 3.9 45.9 1.0
CB A:ALA321 4.0 35.1 1.0
CD2 A:LEU343 4.1 52.1 1.0
C3 A:TQ7502 4.1 63.4 1.0
CG2 A:VAL355 4.1 48.3 1.0
CB A:ILE290 4.2 38.2 1.0
C2 A:TQ7502 4.3 65.1 1.0
CD1 A:ILE236 4.5 45.8 1.0
CG1 A:VAL355 4.5 45.9 1.0
CD1 A:LEU343 4.7 50.9 1.0
CG1 A:ILE290 4.7 41.2 1.0
CD2 A:LEU323 4.7 44.4 1.0
CG2 A:ILE236 4.9 44.5 1.0
CD1 A:TYR159 4.9 46.7 1.0
CG1 A:ILE236 4.9 43.0 1.0
CB A:VAL355 5.0 48.2 1.0

Reference:

L.Halabelian, H.Zeng, A.Dong, M.Schapira, R.F.De Freitas, A.Hutchinson, A.Seitova, C.Bountra, A.M.Edwards, C.H.Arrowsmith, P.J.Brown, Structural Genomics Consortium (Sgc). Crystal Structure of Human Protein Arginine N-Methyltransferase 6 (PRMT6) in Complex with MT2739 Inhibitor To Be Published.
Page generated: Mon Jul 7 10:39:58 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy