Atomistry » Bromine » PDB 6yod-7akh » 6yvw
Atomistry »
  Bromine »
    PDB 6yod-7akh »
      6yvw »

Bromine in PDB 6yvw: Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328

Enzymatic activity of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328

All present enzymatic activity of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328:
1.14.11.29;

Protein crystallography data

The structure of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328, PDB code: 6yvw was solved by R.Chowdhury, B.Banerji, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 18.45 / 1.97
Space group P 63
Cell size a, b, c (Å), α, β, γ (°) 110.175, 110.175, 39.791, 90, 90, 120
R / Rfree (%) 18.7 / 20.8

Other elements in 6yvw:

The structure of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328 also contains other interesting chemical elements:

Iron (Fe) 1 atom

Bromine Binding Sites:

The binding sites of Bromine atom in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328 (pdb code 6yvw). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328, PDB code: 6yvw:

Bromine binding site 1 out of 1 in 6yvw

Go back to Bromine Binding Sites List in 6yvw
Bromine binding site 1 out of 1 in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Monocyclic Bb- 328 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br502

b:75.3
occ:1.00
 BR1 A:PW5502 0.0 75.3 1.0
CAQ A:PW5502 2.0 122.7 1.0
HAB3 A:PW5502 2.8 107.1 1.0
HAA3 A:PW5502 2.8 132.0 1.0
CAN A:PW5502 2.9 110.0 1.0
CAO A:PW5502 3.0 97.0 1.0
HAA1 A:PW5502 3.1 132.0 1.0
CAA A:PW5502 3.1 110.0 1.0
CAB A:PW5502 3.2 89.2 1.0
HAB2 A:PW5502 3.4 107.1 1.0
HH A:TYR310 3.5 49.1 1.0
OH A:TYR310 3.5 40.9 1.0
O A:HOH613 3.5 43.8 1.0
HAA2 A:PW5502 4.1 132.0 1.0
HAB1 A:PW5502 4.1 107.1 1.0
CAG A:PW5502 4.1 89.4 1.0
O A:HOH623 4.1 47.3 1.0
NAJ A:PW5502 4.2 78.6 1.0
O A:HOH649 4.6 45.5 1.0
CAP A:PW5502 4.7 77.5 1.0
CZ A:TYR310 4.7 42.0 1.0
O A:HOH614 4.8 74.8 1.0
HAG1 A:PW5502 4.9 107.4 1.0

Reference:

R.Chowdhury, M.I.Abboud, T.E.Mcallister, B.Banerji, B.Bhushan, J.L.Sorensen, A.Kawamura, C.J.Schofield. Use of Cyclic Peptides to Induce Crystallization: Case Study with Prolyl Hydroxylase Domain 2. Sci Rep V. 10 21964 2020.
ISSN: ESSN 2045-2322
PubMed: 33319810
DOI: 10.1038/S41598-020-76307-8
Page generated: Mon Jul 7 10:47:09 2025

Last articles

Zn in 9QM9
Zn in 9S44
Zn in 9OFE
Zn in 9OFC
Zn in 9OFD
Zn in 9OF1
Zn in 9OFB
Zn in 9N0J
Zn in 9M5X
Zn in 9LGI
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy