Bromine in PDB 7dw5: Crystal Structure of DUX4 HD1-HD2 Domain Complexed with Erg Sites

The structure of Crystal Structure of DUX4 HD1-HD2 Domain Complexed with Erg Sites, PDB code: 7dw5 was solved by H.Zhang, N.Cheng, Z.Li, W.Zhang, X.Dong, J.Huang, G.Meng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.70 / 2.83
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	42.974, 64.451, 69.432, 95.82, 92.55, 103.31
R / Rfree (%)	22.3 / 24.2

The binding sites of Bromine atom in the Crystal Structure of DUX4 HD1-HD2 Domain Complexed with Erg Sites (pdb code 7dw5). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of DUX4 HD1-HD2 Domain Complexed with Erg Sites, PDB code: 7dw5:

Bromine binding site 1 out of 1 in the Crystal Structure of DUX4 HD1-HD2 Domain Complexed with Erg Sites


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of DUX4 HD1-HD2 Domain Complexed with Erg Sites within 5.0Å range: probe atom residue distance (Å) B Occ E:Br101 b:72.4 occ:1.00 H5'' E:DA16 3.8 57.6 1.0 C5' E:DA16 4.7 47.1 1.0 O5' E:DA16 4.9 50.0 1.0

H.Zhang, N.Cheng, Z.Li, L.Bai, C.Fang, Y.Li, W.Zhang, X.Dong, M.Jiang, Y.Liang, S.Zhang, J.Mi, J.Zhu, Y.Zhang, S.J.Chen, Y.Zhao, X.Q.Weng, W.Hu, Z.Chen, J.Huang, G.Meng. Dna Crosslinking and Recombination-Activating Genes 1/2 (RAG1/2) Are Required For Oncogenic Splicing in Acute Lymphoblastic Leukemia. Cancer Commun (Lond) 2021.
ISSN: ISSN 2523-3548
PubMed: 34699692
DOI: 10.1002/CAC2.12234