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Bromine in PDB 7ex4: Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
Enzymatic activity of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
All present enzymatic activity of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5:
2.7.7.48;
2.7.7.48;
Protein crystallography data
The structure of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5, PDB code: 7ex4
was solved by
W.Kuang,
Z.Hu,
P.Gong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 35.41 / 2.00 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 40.933, 70.566, 70.882, 90, 90, 90 |
| R / Rfree (%) | 20.5 / 23.6 |
Other elements in 7ex4:
The structure of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5 also contains other interesting chemical elements:
| Chlorine | (Cl) | 3 atoms |
| Manganese | (Mn) | 2 atoms |
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
(pdb code 7ex4). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5, PDB code: 7ex4:
In total only one binding site of Bromine was determined in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5, PDB code: 7ex4:
Bromine binding site 1 out of 1 in 7ex4
Go back to
Bromine Binding Sites List in 7ex4
Bromine binding site 1 out
of 1 in the Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Crystal Structure of Ebinur Lake Virus Cap Snatching Endonuclease in Complex with Inhibitor 5 within 5.0Å range:
|
Reference:
W.Kuang,
H.Zhang,
Y.Cai,
G.Zhang,
F.Deng,
H.Li,
Y.Zhou,
M.Wang,
P.Gong,
Y.Guo,
Z.Hu.
Structural and Biochemical Basis For Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ). J.Virol. V. 96 17321 2022.
ISSN: ESSN 1098-5514
PubMed: 35266805
DOI: 10.1128/JVI.02173-21
Page generated: Mon Jul 7 11:13:50 2025
ISSN: ESSN 1098-5514
PubMed: 35266805
DOI: 10.1128/JVI.02173-21
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