Atomistry » Bromine » PDB 7i1d-7md6 » 7km7
Atomistry »
  Bromine »
    PDB 7i1d-7md6 »
      7km7 »

Bromine in PDB 7km7: Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From

Enzymatic activity of Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From

All present enzymatic activity of Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From:
1.5.1.3;

Protein crystallography data

The structure of Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From, PDB code: 7km7 was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.66 / 1.80
Space group P 41 2 2
Cell size a, b, c (Å), α, β, γ (°) 59.13, 59.13, 129.49, 90, 90, 90
R / Rfree (%) 17.7 / 20.9

Other elements in 7km7:

The structure of Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From also contains other interesting chemical elements:

Fluorine (F) 2 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From (pdb code 7km7). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From, PDB code: 7km7:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in 7km7

Go back to Bromine Binding Sites List in 7km7
Bromine binding site 1 out of 2 in the Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br203

b:33.1
occ:0.50
 O A:HOH394 3.2 29.2 1.0
CG A:PRO27 4.0 26.9 1.0
O A:HOH445 4.2 33.7 1.0
CD A:PRO27 4.3 24.6 1.0
CA A:PRO27 4.3 21.9 1.0
N A:PRO27 4.3 23.9 1.0
CD2 A:LEU30 4.4 33.3 1.0
CD A:ARG25 4.4 22.2 1.0
CB A:ARG25 4.4 22.6 1.0
CB A:PRO27 4.5 26.6 1.0
N A:LEU26 4.8 23.2 1.0
C A:LEU26 4.8 24.9 1.0
CG A:ARG25 4.9 23.1 1.0

Bromine binding site 2 out of 2 in 7km7

Go back to Bromine Binding Sites List in 7km7
Bromine binding site 2 out of 2 in the Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal From within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br204

b:33.5
occ:0.77
 O A:HOH380 3.1 31.4 1.0
O A:HOH394 3.7 29.2 1.0
NH1 A:ARG25 3.9 29.4 1.0
O A:HOH397 4.0 36.6 1.0
C18 A:WPD202 4.1 25.9 1.0
CD A:ARG25 4.1 22.2 1.0
CZ A:ARG25 4.2 24.4 1.0
C17 A:WPD202 4.2 21.4 1.0
O A:HOH411 4.2 33.6 1.0
CD1 A:ILE22 4.2 26.6 1.0
NE A:ARG25 4.3 27.3 1.0
CD1 A:LEU30 4.3 29.6 1.0
CB A:ILE22 4.4 19.2 1.0
O A:TRP24 4.5 21.4 1.0
CD2 A:LEU30 4.6 33.3 1.0
CG1 A:ILE22 4.7 25.1 1.0
CG A:LEU30 5.0 25.5 1.0

Reference:

J.Abendroth, D.M.Dranow, D.D.Lorimer, P.S.Horanyi, T.E.Edwards. Crystal Structure of Dihydrofolate Reductase (Dhfr) From Mycobacterium Ulcerans AGY99 in Complex with Nadp and Inhibitor Sddc-0001914, Tetragonal Crystal Form To Be Published.
Page generated: Mon Jul 7 11:25:42 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy