Bromine in PDB 9je0: Human URAT1 Bound to Benzbromarone

The binding sites of Bromine atom in the Human URAT1 Bound to Benzbromarone (pdb code 9je0). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Human URAT1 Bound to Benzbromarone, PDB code: 9je0:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Human URAT1 Bound to Benzbromarone


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Human URAT1 Bound to Benzbromarone within 5.0Å range: probe atom residue distance (Å) B Occ A:Br601 b:102.3 occ:1.00 BR1 A:R75601 0.0 102.3 1.0 CAD A:R75601 1.9 102.3 1.0 CAC A:R75601 2.9 102.3 1.0 CAE A:R75601 2.9 102.3 1.0 OAG A:R75601 3.1 102.3 1.0 CE2 A:PHE360 3.4 93.1 1.0 CA A:GLY361 3.6 90.8 1.0 CE2 A:PHE365 3.7 84.1 1.0 CB A:ALA476 3.8 91.7 1.0 CD2 A:PHE360 3.8 93.1 1.0 O A:ALA476 4.1 91.7 1.0 CAB A:R75601 4.2 102.3 1.0 CAF A:R75601 4.2 102.3 1.0 CD2 A:PHE365 4.2 84.1 1.0 CZ A:PHE360 4.2 93.1 1.0 N A:GLY361 4.3 90.8 1.0 C A:ALA476 4.4 91.7 1.0 CA A:ALA476 4.6 91.7 1.0 CAA A:R75601 4.7 102.3 1.0 C A:GLY361 4.8 90.8 1.0 CZ A:PHE365 4.9 84.1 1.0 CG A:PHE360 4.9 93.1 1.0 N A:ARG477 5.0 92.3 1.0

Bromine binding site 2 out of 2 in the Human URAT1 Bound to Benzbromarone


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Human URAT1 Bound to Benzbromarone within 5.0Å range: probe atom residue distance (Å) B Occ A:Br601 b:102.3 occ:1.00 BR2 A:R75601 0.0 102.3 1.0 CAB A:R75601 1.9 102.3 1.0 CAC A:R75601 2.9 102.3 1.0 CAA A:R75601 2.9 102.3 1.0 OAG A:R75601 3.1 102.3 1.0 CG2 A:ILE156 3.7 76.5 1.0 NH1 A:ARG477 3.9 92.3 1.0 SD A:MET214 3.9 88.7 1.0 CG A:ARG477 4.0 92.3 1.0 CD A:ARG477 4.1 92.3 1.0 CAD A:R75601 4.2 102.3 1.0 CAF A:R75601 4.2 102.3 1.0 CAE A:R75601 4.7 102.3 1.0 CD1 A:ILE156 4.9 76.5 1.0 CZ A:ARG477 4.9 92.3 1.0 NE A:ARG477 5.0 92.3 1.0

C.Wu, C.Zhang, S.Jin, J.J.Wang, A.Dai, J.Xu, H.Zhang, X.Yang, X.He, Q.Yuan, W.Hu, Y.Xu, M.Wang, Y.Jiang, D.Yang, H.E.Xu. Molecular Mechanisms of Uric Acid Transport By the Native Human URAT1 and Its Inhibition By Anti-Gout Drugs Biorxiv 2024.
ISSN: ISSN 2692-8205
DOI: 10.1101/2024.09.11.612394