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Atomistry » Bromine » PDB 3x41-4alu » 4a30 » |
Bromine in PDB 4a30: Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide LigandEnzymatic activity of Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand
All present enzymatic activity of Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand:
2.3.1.97; Protein crystallography data
The structure of Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand, PDB code: 4a30
was solved by
D.A.Robinson,
S.Brand,
A.H.Fairlamb,
M.A.J.Ferguson,
J.A.Frearson,
P.G.Wyatt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4a30:
The structure of Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand
(pdb code 4a30). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand, PDB code: 4a30: Bromine binding site 1 out of 1 in 4a30Go back to Bromine Binding Sites List in 4a30
Bromine binding site 1 out
of 1 in the Crystal Structure of Leishmania Major N-Myristoyltransferase (Nmt) with Bound Myristoyl-Coa and A Pyrazole Sulphonamide Ligand
Mono view Stereo pair view
Reference:
S.Brand,
L.A.Cleghorn,
S.P.Mcelroy,
D.A.Robinson,
V.C.Smith,
I.Hallyburton,
J.R.Harrison,
N.R.Norcross,
D.Spinks,
T.Bayliss,
S.Norval,
L.Stojanovski,
L.S.Torrie,
J.A.Frearson,
R.Brenk,
A.H.Fairlamb,
M.A.Ferguson,
K.D.Read,
P.G.Wyatt,
I.H.Gilbert.
Discovery of A Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors. J. Med. Chem. V. 55 140 2012.
Page generated: Sat Dec 12 02:17:12 2020
ISSN: ISSN 1520-4804 PubMed: 22148754 DOI: 10.1021/JM201091T |
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