Bromine in PDB 4a3i: Rna Polymerase II Binary Complex with Dna

All present enzymatic activity of Rna Polymerase II Binary Complex with Dna:
2.7.7.6;

The structure of Rna Polymerase II Binary Complex with Dna, PDB code: 4a3i was solved by A.C.M.Cheung, S.Sainsbury, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.80 / 3.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	221.140, 393.180, 282.480, 90.00, 90.00, 90.00
R / Rfree (%)	15.9 / 19.1

The structure of Rna Polymerase II Binary Complex with Dna also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	8 atoms

The binding sites of Bromine atom in the Rna Polymerase II Binary Complex with Dna (pdb code 4a3i). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Rna Polymerase II Binary Complex with Dna, PDB code: 4a3i:

Bromine binding site 1 out of 1 in the Rna Polymerase II Binary Complex with Dna


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Rna Polymerase II Binary Complex with Dna within 5.0Å range: probe atom residue distance (Å) B Occ T:Br22 b:0.5 occ:1.00 BR T:BRU22 0.0 0.5 1.0 C5 T:BRU22 2.0 0.5 1.0 C6 T:BRU22 2.9 0.5 1.0 C4 T:BRU22 3.1 0.6 1.0 O4 T:BRU22 3.4 0.2 1.0 N7 T:DA21 3.7 0.3 1.0 C5 T:DA21 3.7 0.7 1.0 OE2 B:GLU1120 3.8 0.3 1.0 C8 T:DA21 3.9 0.3 1.0 C4 T:DA21 4.0 0.7 1.0 N9 T:DA21 4.1 0.6 1.0 C6 T:DA21 4.3 0.5 1.0 N1 T:BRU22 4.3 0.6 1.0 N3 T:BRU22 4.3 0.6 1.0 CD B:GLU1120 4.4 0.3 1.0 OE1 B:GLU1120 4.5 0.6 1.0 N6 T:DA21 4.7 0.2 1.0 C3' T:DA21 4.7 0.7 1.0 N3 T:DA21 4.7 0.8 1.0 C2' T:DA21 4.8 0.1 1.0 C2 T:BRU22 4.8 0.5 1.0 N1 T:DA21 4.9 0.5 1.0 OP2 T:BRU22 4.9 0.7 1.0 C1' T:DA21 5.0 0.8 1.0

A.C.Cheung, S.Sainsbury, P.Cramer. Structural Basis of Initial Rna Polymerase II Transcription. Embo J. V. 30 4755 2011.
ISSN: ESSN 1460-2075
PubMed: 22056778
DOI: 10.1038/EMBOJ.2011.396