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Atomistry » Bromine » PDB 4alv-4d46 » 4alw | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 4alv-4d46 » 4alw » |
Bromine in PDB 4alw: Benzofuropyrimidinone Inhibitors of Pim-1Enzymatic activity of Benzofuropyrimidinone Inhibitors of Pim-1
All present enzymatic activity of Benzofuropyrimidinone Inhibitors of Pim-1:
2.7.1.37; Protein crystallography data
The structure of Benzofuropyrimidinone Inhibitors of Pim-1, PDB code: 4alw
was solved by
T.J.Stout,
L.Adams,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Benzofuropyrimidinone Inhibitors of Pim-1
(pdb code 4alw). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Benzofuropyrimidinone Inhibitors of Pim-1, PDB code: 4alw: Bromine binding site 1 out of 1 in 4alwGo back to Bromine Binding Sites List in 4alw
Bromine binding site 1 out
of 1 in the Benzofuropyrimidinone Inhibitors of Pim-1
Mono view Stereo pair view
Reference:
A.L.Tsuhako,
D.S.Brown,
E.S.Koltun,
N.Aay,
A.Arcalas,
V.Chan,
H.Du,
S.Engst,
M.Franzini,
A.Galan,
P.Huang,
S.Johnston,
B.Kane,
M.H.Kim,
A.D.Laird,
R.Lin,
L.Mock,
I.Ngan,
M.Pack,
G.Stott,
T.J.Stout,
P.Yu,
C.Zaharia,
W.Zhang,
P.Zhou,
J.M.Nuss,
P.C.Kearney,
W.Xu.
The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett. V. 22 3732 2012.
Page generated: Sat Dec 12 02:18:08 2020
ISSN: ISSN 0960-894X PubMed: 22542012 DOI: 10.1016/J.BMCL.2012.04.025 |
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