Bromine in PDB 4c8u: Xenopus ZNRF3 Ectodomain Crystal Form II

The structure of Xenopus ZNRF3 Ectodomain Crystal Form II, PDB code: 4c8u was solved by M.Zebisch, E.Y.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.34 / 3.01
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	58.388, 67.410, 75.682, 90.00, 90.00, 90.00
R / Rfree (%)	28.078 / 35.132

The binding sites of Bromine atom in the Xenopus ZNRF3 Ectodomain Crystal Form II (pdb code 4c8u). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Xenopus ZNRF3 Ectodomain Crystal Form II, PDB code: 4c8u:

Bromine binding site 1 out of 1 in the Xenopus ZNRF3 Ectodomain Crystal Form II


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Xenopus ZNRF3 Ectodomain Crystal Form II within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1182 b:53.4 occ:0.50 OG1 A:THR111 3.2 87.8 1.0 N A:THR111 3.2 84.4 1.0 CD2 A:LEU110 3.6 80.2 1.0 CA A:LEU110 3.7 82.5 1.0 CB A:THR111 3.8 85.5 1.0 CB A:LEU110 4.0 80.9 1.0 C A:LEU110 4.0 85.9 1.0 CA A:THR111 4.1 81.2 1.0 CA A:GLY114 4.1 63.8 1.0 CG A:LEU110 4.4 79.7 1.0 O A:THR111 4.4 88.3 1.0 N A:GLY114 4.5 62.1 1.0 C A:THR111 4.8 80.2 1.0 O A:CYS109 5.0 88.5 1.0

M.Zebisch, Y.Xu, C.Krastev, B.T.Macdonald, M.Chen, R.J.C.Gilbert, X.He, E.Y.Jones. Structural and Molecular Basis of ZNRF3/RNF43 Transmembrane Ubiquitin Ligase Inhibition By the Wnt Agonist R-Spondin. Nat.Commun. V. 4 2787 2013.
ISSN: ISSN 2041-1723
PubMed: 24225776
DOI: 10.1038/NCOMMS3787