Bromine in PDB 4nod: Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation

The structure of Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation, PDB code: 4nod was solved by H.B.Ngo, G.A.Lovely, R.Phillips, D.C.Chan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.64 / 2.90
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	56.372, 82.490, 104.222, 79.86, 85.48, 84.53
R / Rfree (%)	22.1 / 26.7

The binding sites of Bromine atom in the Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation (pdb code 4nod). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation, PDB code: 4nod:
Jump to Bromine binding site number: 1; 2; 3; 4;

Bromine binding site 1 out of 4 in the Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation within 5.0Å range: probe atom residue distance (Å) B Occ C:Br19 b:0.9 occ:1.00 BR C:BRU19 0.0 0.9 1.0 C5 C:BRU19 1.9 0.5 1.0 C6 C:BRU19 2.8 0.3 1.0 C4 C:BRU19 3.0 0.7 1.0 O4 C:BRU19 3.3 0.1 1.0 C8 C:DG18 3.8 0.5 1.0 C2' C:DG18 3.9 0.7 1.0 C7 C:DT20 4.0 98.7 1.0 N7 C:DG18 4.0 0.1 1.0 N9 C:DG18 4.0 0.9 1.0 N1 C:BRU19 4.1 0.8 1.0 N3 C:BRU19 4.2 0.5 1.0 C5 C:DG18 4.4 0.6 1.0 C4 C:DG18 4.4 0.8 1.0 C1' C:DG18 4.5 0.4 1.0 C2 C:BRU19 4.6 0.2 1.0 C5 C:DT20 4.9 0.7 1.0

Bromine binding site 2 out of 4 in the Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation within 5.0Å range: probe atom residue distance (Å) B Occ E:Br19 b:0.7 occ:1.00 BR E:BRU19 0.0 0.7 1.0 C5 E:BRU19 1.9 0.7 1.0 C6 E:BRU19 2.9 0.8 1.0 C4 E:BRU19 3.0 1.0 1.0 O4 E:BRU19 3.2 0.6 1.0 C8 E:DG18 3.8 0.1 1.0 C7 E:DT20 4.0 0.1 1.0 N7 E:DG18 4.0 0.9 1.0 C2' E:DG18 4.0 0.2 1.0 N9 E:DG18 4.1 0.9 1.0 N1 E:BRU19 4.1 0.4 1.0 N3 E:BRU19 4.2 0.5 1.0 C5 E:DG18 4.4 0.8 1.0 C4 E:DG18 4.5 0.7 1.0 C1' E:DG18 4.6 0.5 1.0 C2 E:BRU19 4.7 0.4 1.0 C5 E:DT20 4.9 0.5 1.0 O4 E:DT20 4.9 0.4 1.0

Bromine binding site 3 out of 4 in the Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation within 5.0Å range: probe atom residue distance (Å) B Occ I:Br19 b:0.4 occ:1.00 BR I:BRU19 0.0 0.4 1.0 C5 I:BRU19 1.9 0.4 1.0 C6 I:BRU19 2.8 1.0 1.0 C4 I:BRU19 3.0 0.9 1.0 O4 I:BRU19 3.3 0.9 1.0 C8 I:DG18 3.7 0.1 1.0 C2' I:DG18 3.9 0.6 1.0 C7 I:DT20 4.0 73.6 1.0 N9 I:DG18 4.0 0.4 1.0 N7 I:DG18 4.0 97.2 1.0 N1 I:BRU19 4.1 0.8 1.0 N3 I:BRU19 4.2 96.6 1.0 C5 I:DG18 4.4 95.3 1.0 C4 I:DG18 4.4 95.1 1.0 C1' I:DG18 4.5 1.0 1.0 C2 I:BRU19 4.6 0.4 1.0 C5 I:DT20 4.9 75.0 1.0

Bromine binding site 4 out of 4 in the Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation within 5.0Å range: probe atom residue distance (Å) B Occ K:Br19 b:0.9 occ:1.00 BR K:BRU19 0.0 0.9 1.0 C5 K:BRU19 1.9 0.6 1.0 C6 K:BRU19 2.8 0.1 1.0 C4 K:BRU19 3.0 0.5 1.0 O4 K:BRU19 3.2 0.1 1.0 C8 K:DG18 3.7 0.5 1.0 C2' K:DG18 3.9 0.2 1.0 N7 K:DG18 4.0 0.9 1.0 N9 K:DG18 4.0 0.1 1.0 C7 K:DT20 4.0 76.1 1.0 N1 K:BRU19 4.1 0.5 1.0 N3 K:BRU19 4.2 0.1 1.0 C5 K:DG18 4.4 0.3 1.0 C4 K:DG18 4.4 0.2 1.0 C1' K:DG18 4.5 0.2 1.0 C2 K:BRU19 4.6 0.4 1.0 C5 K:DT20 4.9 78.4 1.0

H.B.Ngo, G.A.Lovely, R.Phillips, D.C.Chan. Distinct Structural Features of Tfam Drive Mitochondrial Dna Packaging Versus Transcriptional Activation. Nat Commun V. 5 3077 2014.
ISSN: ESSN 2041-1723
PubMed: 24435062
DOI: 10.1038/NCOMMS4077